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FKBP25/FKBP3 Protein, Human, Recombinant (His)

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货号 TMPJ-01068

别名 Rotamase, Rapamycin-selective 25 kDa immunophilin, PPIase FKBP3, Peptidyl-prolyl cis-trans isomerase FKBP3, Immunophilin FKBP25, FKBP-3, FKBP-25, FKBP25, FK506-binding protein 3, 25 kDa FKBP, 25 kDa FK506-binding protein

FKBP25 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

FKBP25/FKBP3 Protein, Human, Recombinant (His)

FKBP25/FKBP3 Protein, Human, Recombinant (His)

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Rating icon 还可以
货号 TMPJ-01068 别名 Rotamase, Rapamycin-selective 25 kDa immunophilin, PPIase FKBP3, Peptidyl-prolyl cis-trans isomerase FKBP3, Immunophilin FKBP25, FKBP-3, FKBP-25, FKBP25, FK506-binding protein 3, 25 kDa FKBP, 25 kDa FK506-binding protein

FKBP25 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

规格价格库存数量
5 μg
¥ 243
6-8日内发货
10 μg
¥ 380
6-8日内发货
20 μg
¥ 525
5日内发货
50 μg
¥ 820
5日内发货
100 μg
¥ 1,380
5日内发货
200 μg
¥ 2,430
5日内发货
500 μg
¥ 5,130
5日内发货
1 mg
¥ 8,300
5日内发货
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产品介绍


生物活性
产品描述
FKBP25 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
FKBP25 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
种属
Human
表达系统
E. coli
标签N-6xHis
蛋白编号Q00688
氨基酸序列Met1-Asp224
蛋白构建Met1-Asp224
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 1 mM DTT, 10% Glycerol, pH 8.0.
别名Rotamase, Rapamycin-selective 25 kDa immunophilin, PPIase FKBP3, Peptidyl-prolyl cis-trans isomerase FKBP3, Immunophilin FKBP25, FKBP-3, FKBP-25, FKBP25, FK506-binding protein 3, 25 kDa FKBP, 25 kDa FK506-binding protein
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量30 KDa (reducing condition)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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