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Anti-LY75 Antibody (7T586) 是一种 Rabbit 抗体,靶向 LY75。Anti-LY75 Antibody (7T586) 可用于 WB,IHC,IP。
Anti-LY75 Antibody (7T586) 是一种 Rabbit 抗体,靶向 LY75。Anti-LY75 Antibody (7T586) 可用于 WB,IHC,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-LY75 Antibody (7T586) is a Rabbit antibody targeting LY75. Anti-LY75 Antibody (7T586) can be used in WB,IHC,IP. |
别名 | Renal Cell Carcinoma (gp200), Lymphocyte antigen 75, LY75_HUMAN, Ly-75, LY75, LY 75, gp200-MR6, gp200 MR6, gp200, DEC-205, DEC205, DEC 205, C-type lectin domain family 13 member B, CLEC13B, CLEC 13B, CD205 antigen, CD205, CD 205 |
Ig Type | IgG |
交叉反应 | Human,Mouse |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-LY75 antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-LY75 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LY75 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-LY75 antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | DEC-205 (LY75, lymphocyte antigen 75, GP200-MR6) is a 1,695 residue (mature form) multilectin receptor that belongs to the MMR (macrophage mannose receptor) family of multidomain molecules. MMR family molecules mediate membrane receptor targeting to endosomes or lysosomes rich in major histocompatibility complex class II (MHC II) products. Expressed in mature dendritic cells (DC), DEC-205 contains an extracellular N-terminal cysteine-rich domain, a fibronectin type II domain, ten C-type carbohydrate recognition domains, a single transmembrane region and a small cytoplasmic C-terminal domain (31 amino acids) containing a tyrosine at 1679. DEC-205 elicits either an agonistic or antagonistic effect on IL-4 function, which is demonstrated by the ability of DEC-205 to imitate IL-4-induced maturation of epithelium or to inhibit IL-4-induced proliferation of T cells, respectively. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 198 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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