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p67phox Protein, Human, Recombinant

产品编号 TMPY-03660

别名: NCF-2, NOXA2, P67-PHOX, P67PHOX, neutrophil cytosolic factor 2

p67phox Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 30 kDa and the accession number is AAH01606.1.

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p67phox Protein, Human, Recombinant

规格	价格/CNY		货期	数量
100 μg	￥ 3,820		5日内发货

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参考文献

生物活性	Testing in progress
产品描述	p67phox Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 30 kDa and the accession number is AAH01606.1.

种属	Human
表达系统	Baculovirus Insect Cells
标签	Tag Free
蛋白编号	AAH01606.1
别名	NCF-2, NOXA2, P67-PHOX, P67PHOX, neutrophil cytosolic factor 2
蛋白构建	The Human NCF2 (AAH01606.1) (Met1-Val526) was expressed and purified with two additional amino acids (Gly & Pro) at the N-terminus.
蛋白纯度	> 85 % as determined by SDS-PAGE
分子量	30 kDa (predicted)

内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 300 mM NaCl, pH 8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	NCF2 (Neutrophil Cytosolic Factor 2, also known as NCF-2 and p67phox) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. NCF2 belongs to the NCF2/NOXA1 family. NCF2, NCF1, and a membrane-bound cytochrome b558 are required for activation of the latent NADPH oxidase. Mutations in the NCF2 gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.

参考文献

1. Wientjes FB. et al., 1996, Semin Cell Biol. 6 (6): 357-65. 2. DeLeo FR. et al., 1997, J Leukoc Biol. 60 (6): 677-91. 3. Dorseuil O. et al., 1997, C R Seances Soc Biol Fil. 191 (2): 237-46.

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Keywords

p67phox Protein, Human, Recombinant NOXA-2 NCF-2 NCF 2 NOXA2 P67-PHOX NCF2 NOXA 2 P67PHOX neutrophil cytosolic factor 2 recombinant recombinant-proteins proteins protein

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