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Anti-CD163 Antibody (2R634)
还可以产品编号 TMAH-00173
别名 sCD163, SCARI1, RM3/1, MM130, M130, HbSR, GHI/61, CD163 molecule, CD163
Anti-CD163 Antibody (2R634) 是一种抗体，靶向 CD163。Anti-CD163 Antibody (2R634) 可用于 ELISA, IHC。
Anti-CD163 Antibody (2R634)
Anti-CD163 Antibody (2R634)
还可以产品编号 TMAH-00173 别名 sCD163, SCARI1, RM3/1, MM130, M130, HbSR, GHI/61, CD163 molecule, CD163
Anti-CD163 Antibody (2R634) 是一种抗体，靶向 CD163。Anti-CD163 Antibody (2R634) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,310 | 5日内发货 | |
| 100 μL | ¥ 2,195 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CD163 Antibody (2R634) is an antibody targeting CD163. Anti-CD163 Antibody (2R634) can be used in ELISA, IHC. |
| 别名 | sCD163, SCARI1, RM3/1, MM130, M130, HbSR, GHI/61, CD163 molecule, CD163 |
| Ig Type | hIgG1 |
| 克隆号 | 2R634 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-00173 diluted at 1:300 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB. |
| 应用 | ELISA, IHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | [Soluble CD163]: Secreted.; Cell membrane; Single-pass type I membrane protein. Note=Isoform 1 and isoform 2 show a lower surface expression when expressed in cells. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 研究背景 | Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells. After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human CD163 Protein |
| 抗原种属 | Human |
| 基因ID | 9332 |
| Uniprot ID | |
| 研究领域 | Cardiovascular, Immunology |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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