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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-MAP3K7IP1 (Thr431) Polyclonal Antibody

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货号 TMAB-10931

Anti-Phospho-MAP3K7IP1 (Thr431) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-MAP3K7IP1 (Thr431)。Anti-Phospho-MAP3K7IP1 (Thr431) Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Phospho-MAP3K7IP1 (Thr431) Polyclonal Antibody

Anti-Phospho-MAP3K7IP1 (Thr431) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10931

Anti-Phospho-MAP3K7IP1 (Thr431) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-MAP3K7IP1 (Thr431)。Anti-Phospho-MAP3K7IP1 (Thr431) Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-MAP3K7IP1 (Thr431) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAP3K7IP1 (Thr431). Anti-Phospho-MAP3K7IP1 (Thr431) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Ubiquitous.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1/MAP3K7, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta and members of the Toll IL 1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses. This protein, together with either TAB2 or TAB3, activates TAK1 kinase in response to upstream signals. It has been shown that the C terminal portion of TAB1 is sufficient for binding and activation of TAK1, while a portion of the N terminus acts as a dominant negative inhibitor of TGF beta, demonstrating how this protein can function as a mediator between TGF beta receptors and TAK1.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human MAP3K7IP1 around the phosphorylation site of Thr431
抗原种属
Human
基因名称
TAB1
基因ID
10454
蛋白名称
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
Uniprot ID
Q15750
功能
May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis.
化学信息
分子量Theoretical: 56 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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