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Anti-FAM171A2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FAM171A2。Anti-FAM171A2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-FAM171A2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FAM171A2。Anti-FAM171A2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-FAM171A2 Polyclonal Antibody is a Rabbit antibody targeting FAM171A2. Anti-FAM171A2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat,Pig,Cow,Sheep) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | FAM171A2 is a 826 single-pass type I membrane protein belonging to the FAM171 family and is encoded by a gene located on human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair and is specifically recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17. |
| 免疫原 | KLH conjugated synthetic peptide: human FAM171A2 |
| 抗原种属 | Human |
| 基因名称 | FAM171A2 |
| 基因ID | |
| 蛋白名称 | Protein FAM171A2 |
| Uniprot ID |
| 分子量 | Theoretical: 85 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |