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OSMR Protein, Human, Recombinant (His) V2

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产品编号 TMPY-01305U

OSMR Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q99650-1.

OSMR Protein, Human, Recombinant (His) V2

一键复制产品信息

产品编号 TMPY-01305U

OSMR Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q99650-1.

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产品信息

生物活性	Immobilized Human OSMR, His Tag at 1 μg/ml (100 μl/Well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 4.4 ng/ml determined by ELISA.
产品描述	OSMR Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q99650-1.
种属	Human
表达系统	HEK293 Cells
标签	C-His
蛋白编号	Q99650-1
别名	PLCA1,OSMRB,oncostatin M receptor,IL-31RB
蛋白构建	Glu28-Met740
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	82.2 kDa (Predicted); 110-140 kDa (Due to glycosylation)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.