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Anti-IL-2 R gamma/CD132 Antibody (3J53)

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Anti-IL-2 R gamma/CD132 Antibody (3J53)
产品编号 TMAY-03091
别名 γC, SCIDX1, SCIDX, P64, IMD4, IL2RG, IL-2 R γ/CD132, IL-2 R γ, IL-2 R gamma, gammaC, CIDX, CD132

Anti-IL-2 R gamma/CD132 Antibody (3J53) 是一种 Rabbit 抗体，靶向 IL-2 R gamma/CD132。Anti-IL-2 R gamma/CD132 Antibody (3J53) 可用于 ELISA(Cap),FCM,ICC/IF。

Anti-IL-2 R gamma/CD132 Antibody (3J53)

Anti-IL-2 R gamma/CD132 Antibody (3J53)

Rating icon 还可以
Anti-IL-2 R gamma/CD132 Antibody (3J53)
产品编号 TMAY-03091 别名 γC, SCIDX1, SCIDX, P64, IMD4, IL2RG, IL-2 R γ/CD132, IL-2 R γ, IL-2 R gamma, gammaC, CIDX, CD132

Anti-IL-2 R gamma/CD132 Antibody (3J53) 是一种 Rabbit 抗体，靶向 IL-2 R gamma/CD132。Anti-IL-2 R gamma/CD132 Antibody (3J53) 可用于 ELISA(Cap),FCM,ICC/IF。

规格价格库存数量
20 μL
¥ 790
5日内发货
100 μL
¥ 2,294
5日内发货
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产品描述
Anti-IL-2 R gamma/CD132 Antibody (3J53) is a Rabbit antibody targeting IL-2 R gamma/CD132. Anti-IL-2 R gamma/CD132 Antibody (3J53) can be used in ELISA(Cap),FCM,ICC/IF.
别名γC, SCIDX1, SCIDX, P64, IMD4, IL2RG, IL-2 R γ/CD132, IL-2 R γ, IL-2 R gamma, gammaC, CIDX, CD132
Ig Type
Rabbit IgG
克隆号
3J53
交叉反应
Mouse
验证活性
1. Immunofluorescence staining of mouse IL2RG in mouse splenocytes. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-mouse IL2RG monoclonal antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green).
2. Flow cytometric analysis of Mouse IL2RG(CD132) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse IL2RG(CD132), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
ELISA(Cap)
FCM
ICC/IF
推荐剂量
ICC-IF: 1:20-1:100; FCM: 1:25-1:100; ELISA(Cap): 1:250-1:2000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD132 / IL2RG (rM CD132 / IL2RG; TMPY-01837; NP_038591.1; Met1-Ala263).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The common gamma chain (γc) (or CD132), also known as interleukin-2 receptor subunit gamma or IL2RG, is a member of the type I cytokine receptor family expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. The common gamma chain (γc) (or IL2RG), is a cytokine receptor subunit that is common to the receptor complexes for at least six different interleukin receptors: IL-2, IL-4, IL-7, IL-9, IL-15, and the interleukin-21 receptor. It is a component of multiple cytokine receptors that are essential for lymphocyte development and function. X-linked severe combined immunodeficiency (X-SCID) is a rare and potentially fatal disease caused by mutations of IL2RG, the gene encoding IL2RG. IL2RG was demonstrated to be a component of the IL-4 receptor based on chemical cross-linking data, the ability of IL2RG to augment IL-4 binding affinity. The observation that IL-2R gamma is a functional component of the IL-4 receptor, together with the finding that IL-2R gamma associates with the IL-7 receptor, begins to elucidate why a deficiency of this common gamma chain (gamma c) has a profound effect on lymphoid function and development, as seen in X-linked severe combined immunodeficiency.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
PE
可提供抗体种类
2
抗原信息
免疫原
Recombinant Protein: Mouse CD132 / IL2RG Protein (TMPY-01837)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

SCIDX-1SCIDX 1P-64P 64IMD-4IMD 4CD-132CD 132

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