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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-C4 binding protein Polyclonal Antibody

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货号 TMAB-03440

Anti-C4 binding protein Polyclonal Antibody 是一种 Rabbit 抗体，靶向 C4 binding protein。Anti-C4 binding protein Polyclonal Antibody 可用于 WB。

Anti-C4 binding protein Polyclonal Antibody

Anti-C4 binding protein Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-03440

Anti-C4 binding protein Polyclonal Antibody 是一种 Rabbit 抗体，靶向 C4 binding protein。Anti-C4 binding protein Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-C4 binding protein Polyclonal Antibody is a Rabbit antibody targeting C4 binding protein. Anti-C4 binding protein Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Rat,Dog)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants
抗原信息
免疫原
KLH conjugated synthetic peptide: human C4 binding protein
抗原种属
Human
基因名称
C4BPB
基因ID
725
蛋白名称
C4b-binding protein beta chain
Uniprot ID
P20851
功能
Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.
化学信息
分子量Theoretical: 26 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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