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顶部产品介绍化学信息储存和溶解信息计算器技术支持

PD-L2 Protein, Human, Recombinant (His & Avi)

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货号 TMPK-00166

别名 PD-L2, PDL2, PDCD1LG2, PDCD1L2, CD273, PDCD1 ligand 2, Butyrophilin B7-DC, Btdc, bA574F11.2, B7DC

PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. PD-L2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.3 kDa and the accession number is Q9BQ51.

PD-L2 Protein, Human, Recombinant (His & Avi)
其他形式的 “PD-L2 Protein, Human, Recombinant (His & Avi)”:
PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His)
PD-L2 Protein, Human, Recombinant (hFc)
PD-L2 Protein, Mouse, Recombinant (His)
PD-L2 Protein, Mouse, Recombinant (hFc)
PD-L2 Protein, Rat, Recombinant (hFc)
PD-L2 Protein, Rat, Recombinant (His)
PD-L2 Protein, Human, Recombinant (His)
PD-L2 Protein, Human, Recombinant (His), Biotinylated
PD-L2 Protein, Mouse, Recombinant (His), Biotinylated
PD-L2 Protein, Human, Recombinant (His & Avi), Biotinylated
PD-L2 Protein, Human, Recombinant (mFc)
PD-L2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
PD-L2 Protein, Rhesus, Recombinant (hFc)
PD-L2 Protein, Rhesus, Recombinant (His)

PD-L2 Protein, Human, Recombinant (His & Avi)

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Rating icon 还可以
SPR兼容缓冲液
货号 TMPK-00166 别名 PD-L2, PDL2, PDCD1LG2, PDCD1L2, CD273, PDCD1 ligand 2, Butyrophilin B7-DC, Btdc, bA574F11.2, B7DC

PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. PD-L2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.3 kDa and the accession number is Q9BQ51.

规格价格库存数量
5 μg
¥ 253
6-8日内发货
10 μg
¥ 395
6-8日内发货
20 μg
¥ 636
5日内发货
50 μg
¥ 1,230
5日内发货
100 μg
¥ 2,060
5日内发货
200 μg
¥ 3,730
5日内发货
500 μg
¥ 8,300
5日内发货
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产品介绍

生物活性
产品描述
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. PD-L2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.3 kDa and the accession number is Q9BQ51.
生物活性
Human PD-1, hFc Tag captured on CM5 Chip via Protein A can bind Human PD-L2, His Tag with an affinity constant of 0.296 μM as determined in SPR assay.
研究背景
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals.
种属
Human
表达系统
HEK293 Cells
标签C-His-Avi
蛋白编号Q9BQ51
蛋白构建Leu20-Thr220
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名PD-L2, PDL2, PDCD1LG2, PDCD1L2, CD273, PDCD1 ligand 2, Butyrophilin B7-DC, Btdc, bA574F11.2, B7DC
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量25.3 kDa (predicted). Due to glycosylation, the protein migrates to 40-52 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

PDL-2PDL 2
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