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Anti-NEDD8 Antibody (1Q389) 是一种 Rabbit 抗体,靶向 NEDD8。Anti-NEDD8 Antibody (1Q389) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP。
Anti-NEDD8 Antibody (1Q389) 是一种 Rabbit 抗体,靶向 NEDD8。Anti-NEDD8 Antibody (1Q389) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 780 | 5日内发货 | |
| 50 μL | ¥ 1,380 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-NEDD8 Antibody (1Q389) is a Rabbit antibody targeting NEDD8. Anti-NEDD8 Antibody (1Q389) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP. |
| Ig Type | IgG |
| 克隆号 | 1Q389 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBIHC-PIHC-FrICC/IFIFIP |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500; IP: 1:20-50 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. Note=Mainly nuclear. |
| 组织特异性 | Highly expressed in heart, skeletal muscle, spleen, thymus, prostate, testis, ovary, colon and leukocytes. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis via its conjugation to a limited number of cellular proteins, such as cullins or p53/TP53.Attachment of NEDD8 to cullins is critical for the recruitment of E2 to the cullin-RING-based E3 ubiquitin-protein ligase complex, thus facilitating polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. |
| 免疫原 | A synthesized peptide: human NEDD8 |
| 抗原种属 | Human |
| 基因名称 | NEDD8 |
| 基因ID | |
| 蛋白名称 | NEDD8 |
| Uniprot ID | |
| 功能 | Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. |
| 分子量 | Theoretical: 9 kDa. Actual: 10, 90 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |