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Anti-VAPB Antibody (1H529) 是一种 Rabbit 抗体,靶向 VAPB。Anti-VAPB Antibody (1H529) 可用于 WB,ELISA。
Anti-VAPB Antibody (1H529) 是一种 Rabbit 抗体,靶向 VAPB。Anti-VAPB Antibody (1H529) 可用于 WB,ELISA。
产品描述 | Anti-VAPB Antibody (1H529) is a Rabbit antibody targeting VAPB. Anti-VAPB Antibody (1H529) can be used in WB,ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 1H529 |
交叉反应 | Human |
验证活性 | Anti-VAPB rabbit monoclonal antibody at 1:500 dilution. -Lane A: HepG2 Whole Cell Lysate. -Lane B: A549 Whole Cell Lysate. -Lane C: Jurkat Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:27 kDa. -Observed band size:32 kDa |
应用 | WB,ELISA |
推荐剂量 | WB: 1:500-1:2000; ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human VAPB / VAP-B (rh VAPB / VAP-B; TMPY-02196; O95292-1; Met 1-Pro 132). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Vesicle-associated membrane protein-associated protein B / C, also known as VAMP-B/VAMP-C, VAMP-associated protein B/C, VAP-B/VAP-C and VAPB, is a single-pass type IV membrane protein that belongs to the VAMP-associated protein (VAP) family. VAPB contains one MSP domain. VAPB may play a role in vesicle trafficking. VAPB forms a heterodimer with VAPA. VAPB interacts with VAMP1 and VAMP2. Defects in VAPB are the cause of amyotrophic lateral sclerosis type 8 ( ALS8 ) which is a familial form of amyotrophic lateral sclerosis, a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Defects in VAPB are also a cause of spinal muscular atrophy autosomal dominant Finkel type (SMAF) which is characterized by proximal muscle weakness that begins in the lower limbs and then progresses to upper limbs. |
偶联 | Unconjugated |
免疫原 | Recombinant Human VAPB / VAP-B protein (TMPY-02196) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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