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顶部生物活性储存和溶解信息计算器

Anti-BDKRB2 Antibody (4Y573)

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Anti-BDKRB2 Antibody (4Y573)
产品编号 TMAC-00411
别名 Kinin B2 Bradykinin receptor beta 2, DKFZp686O088, BRB2, BRB 2, Bradykinin receptor beta 2, Bradykinin receptor b2, BR B2, BKR2, BKR 2, BK2R, BK2 receptor, BK2, BK R2, BK 2 receptor, BK 2, BDKRB 2, BDKR B2, B2R, B2BRA, B2BKR, B2 bradykinin receptor, B2

Anti-BDKRB2 Antibody (4Y573) 是一种 Rabbit 抗体，靶向 BDKRB2。Anti-BDKRB2 Antibody (4Y573) 可用于 WB,FCM,IP。

Anti-BDKRB2 Antibody (4Y573)

Anti-BDKRB2 Antibody (4Y573)

Rating icon 还可以
Anti-BDKRB2 Antibody (4Y573)
产品编号 TMAC-00411 别名 Kinin B2 Bradykinin receptor beta 2, DKFZp686O088, BRB2, BRB 2, Bradykinin receptor beta 2, Bradykinin receptor b2, BR B2, BKR2, BKR 2, BK2R, BK2 receptor, BK2, BK R2, BK 2 receptor, BK 2, BDKRB 2, BDKR B2, B2R, B2BRA, B2BKR, B2 bradykinin receptor, B2

Anti-BDKRB2 Antibody (4Y573) 是一种 Rabbit 抗体，靶向 BDKRB2。Anti-BDKRB2 Antibody (4Y573) 可用于 WB,FCM,IP。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-BDKRB2 Antibody (4Y573) is a Rabbit antibody targeting BDKRB2. Anti-BDKRB2 Antibody (4Y573) can be used in WB,FCM,IP.
别名Kinin B2 Bradykinin receptor beta 2, DKFZp686O088, BRB2, BRB 2, Bradykinin receptor beta 2, Bradykinin receptor b2, BR B2, BKR2, BKR 2, BK2R, BK2 receptor, BK2, BK R2, BK 2 receptor, BK 2, BDKRB 2, BDKR B2, B2R, B2BRA, B2BKR, B2 bradykinin receptor, B2
Ig Type
IgG
交叉反应
Human,Mouse
验证活性
1. Western blot analysis of BDKRB2 on MCF-7 cell lysate using anti-BDKRB2 antibody at 1/500 dilution.
2. Flow cytometric analysis of SH-SY5Y cells with BDKRB2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
应用
WB
FCM
IP
推荐剂量
WB: 1:500-1000; IP: 1:10-50; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Kinins are important biologically active peptides that mediate cardiovascular homeostasis, inflammation and nociception. Bradykinin, the major effector peptide of the kallikrein-kinin system, is regulated by angiotensin-converting enzyme (ACE), which degrades the peptide. Bradykinin normally exerts its effects through the activation of two seven transmembrane G-protein coupled receptors, named B1 and B2. The B2 receptor is constitutively expressed and preferentially binds full length bradykinin. Deletion of the B2 receptor leads to salt-sensitive hypertension and altered nociception in mice. The B1 receptor binds to derivatives of bradykinin and kallidin, which are produced by carboxypeptidase action to generate the products des-Arg9-bradykinin and des-Arg10-kallidin, respectively. The expression of the B1 receptor is inducible by inflammatory mediators, such as bacterial lipopolysaccharide (LPS) and cytokines. The B1 and B2 receptors represent potential therapeutic targets for treatment of inflammatory disorders and cardiovascular diseases.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P30411
化学信息
分子量Theoretical: 80 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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