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Anti-Phospho-Merlin (Ser518) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Merlin (Ser518)。Anti-Phospho-Merlin (Ser518) Polyclonal Antibody 可用于 WB,IF。
Anti-Phospho-Merlin (Ser518) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Merlin (Ser518)。Anti-Phospho-Merlin (Ser518) Polyclonal Antibody 可用于 WB,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,230 | 5日内发货 |
产品描述 | Anti-Phospho-Merlin (Ser518) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Merlin (Ser518). Anti-Phospho-Merlin (Ser518) Polyclonal Antibody can be used in WB,IF. |
别名 | p-Merlin (Ser518), p-Merlin (S518), Merlin (p-Ser518), Merlin (p-S518) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of extracts from HUVEC cells untreated (lane 1) or treated with IFN-a (lane 2) using Merlin (Phospho-Ser518) Antibody TMAC-02562. 2. Immunofluorescence staining of methanol-fixed Hela cells using Merlin (Phospho-Ser518) Antibody TMAC-02562. 3. Western blot analysis of extracts from C6 cells, treated with calf intestinal phosphatase (CIP), using Merlin (Phospho-Ser518) Antibody TMAC-02562. |
应用 | |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of serine 518 (R-L-S(p)-M-E) derived from Human Merlin |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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