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Anti-Phospho-Merlin (Ser518) Polyclonal Antibody 2

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Anti-Phospho-Merlin (Ser518) Polyclonal Antibody 2
产品编号 TMAC-02562
别名 p-Merlin (Ser518), p-Merlin (S518), Merlin (p-Ser518), Merlin (p-S518)

Anti-Phospho-Merlin (Ser518) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Merlin (Ser518)。Anti-Phospho-Merlin (Ser518) Polyclonal Antibody 可用于 WB,IF。

Anti-Phospho-Merlin (Ser518) Polyclonal Antibody 2

Anti-Phospho-Merlin (Ser518) Polyclonal Antibody 2

Rating icon 还可以
Anti-Phospho-Merlin (Ser518) Polyclonal Antibody 2
产品编号 TMAC-02562 别名 p-Merlin (Ser518), p-Merlin (S518), Merlin (p-Ser518), Merlin (p-S518)

Anti-Phospho-Merlin (Ser518) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Merlin (Ser518)。Anti-Phospho-Merlin (Ser518) Polyclonal Antibody 可用于 WB,IF。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,230
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Merlin (Ser518) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Merlin (Ser518). Anti-Phospho-Merlin (Ser518) Polyclonal Antibody can be used in WB,IF.
别名p-Merlin (Ser518), p-Merlin (S518), Merlin (p-Ser518), Merlin (p-S518)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from HUVEC cells untreated (lane 1) or treated with IFN-a (lane 2) using Merlin (Phospho-Ser518) Antibody TMAC-02562.
2. Immunofluorescence staining of methanol-fixed Hela cells using Merlin (Phospho-Ser518) Antibody TMAC-02562.
3. Western blot analysis of extracts from C6 cells, treated with calf intestinal phosphatase (CIP), using Merlin (Phospho-Ser518) Antibody TMAC-02562.
应用
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of serine 518 (R-L-S(p)-M-E) derived from Human Merlin
抗原种属
human
Uniprot ID
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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