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Anti-HE4 Antibody (2E375)

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Anti-HE4 Antibody (2E375)
产品编号 TMAY-02398
别名 WAP four-disulfide core domain 2

Anti-HE4 Antibody (2E375) 是一种 Rabbit 抗体,靶向 HE4。Anti-HE4 Antibody (2E375) 可用于 IHC-P。

Anti-HE4 Antibody (2E375)

Anti-HE4 Antibody (2E375)

Rating icon 还可以
Anti-HE4 Antibody (2E375)
产品编号 TMAY-02398 别名 WAP four-disulfide core domain 2

Anti-HE4 Antibody (2E375) 是一种 Rabbit 抗体,靶向 HE4。Anti-HE4 Antibody (2E375) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-HE4 Antibody (2E375) is a Rabbit antibody targeting HE4. Anti-HE4 Antibody (2E375) can be used in IHC-P.
别名WAP four-disulfide core domain 2
Ig Type
Rabbit IgG
克隆号
2E375
交叉反应
Human
验证活性
1. Immunochemical staining of human WFDC2 in human ovarian cancer (from 7 donors) with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to the malignant cell.
2. Immunochemical staining of human WFDC2 in human endometrium with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to the epithelium of uterune gland.
应用
推荐剂量
IHC-P: 1:100-1:500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human WFDC2 / HE4 (rh WFDC2 / HE4; TMPY-01882; NP_006094.3; Met1-Phe124).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景WAP four-disulfide core domain protein 2, also known as Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, WFDC2 and HE4, is a secreted protein that contains two WAP domains. WFDC2 / HE4 is a member of a family of stable 4-disulfide core proteins that are secreted at high levels. It is expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. It is highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. WFDC2 may be a component of the innate immune defences of the lung, nasal and oral cavities and suggest that WFDC2 functions in concert with related WAP domain containing proteins in epithelial host defence. WFDC2 re-expression in lung carcinomas may prove to be associated with tumour type and should be studied in further detail. Mammary gland expression of tammar WFDC2 during the course of lactation showed WFDC2 was elevated during pregnancy, reduced in early lactation and absent in mid-late lactation. WFDC2 / HE4 can undergo a complex series of alternative splicing events that can potentially yield five distinct WAP domain containing protein isoforms.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human WFDC2 / HE4 protein (TMPY-01882)
抗原种属
Human
研究领域
Serine Proteases and Regulators
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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