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Anti-Iba1 Antibody (3Y490)
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产品编号 TMAY-02698
别名 IRT-1, IRT1, IBA1, allograft inflammatory factor 1, AIF-1
Anti-Iba1 Antibody (3Y490) 是一种 Rabbit 抗体，靶向 Iba1。Anti-Iba1 Antibody (3Y490) 可用于 ELISA,IHC-P,ICC/IF。
Anti-Iba1 Antibody (3Y490)
331 Anti-Iba1 Antibody (3Y490)
还可以产品编号 TMAY-02698 别名 IRT-1, IRT1, IBA1, allograft inflammatory factor 1, AIF-1
Anti-Iba1 Antibody (3Y490) 是一种 Rabbit 抗体，靶向 Iba1。Anti-Iba1 Antibody (3Y490) 可用于 ELISA,IHC-P,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 790 | 5日内发货 | |
| 100 μL | ¥ 2,284 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Iba1 Antibody (3Y490) is a Rabbit antibody targeting Iba1. Anti-Iba1 Antibody (3Y490) can be used in ELISA,IHC-P,ICC/IF. |
| 别名 | IRT-1, IRT1, IBA1, allograft inflammatory factor 1, AIF-1 |
| Ig Type | Rabbit IgG |
| 克隆号 | 3Y490 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human AIF1 in human spleen with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human AIF1 in human brain with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 3. Immunofluorescence staining of AIF1 in K562 cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-human AIF1 monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Cytoplasm and Cell membrane. |
| 应用 | ELISA,IHC-P,ICC/IF |
| 推荐剂量 | ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500; ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human IBA1 / AIF1 (rh IBA1 / AIF1; TMPY-03337; P55008-1; Met1-Pro147). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | AIF1, also known as IBA1, is an actin-binding protein. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68(+) macrophages in the interstitial and perivascular spaces of human heart allografts. It is expressed in macrophages and neutrophils. AIF1 enhances membrane ruffling and RAC activation. AIF1 enhances the actin-bundling activity of LCP1. It also enhances lymphocyte migration. AIF1 may play a role in macrophage activation and function. It binds calcium and plays a role in RAC signaling and in phagocytosis. It promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human IBA1 / AIF1 Protein (TMPY-03337) |
| 抗原种属 | Human |
| 研究领域 | Calcium-binding Proteins and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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