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Anti-GPRC5D Antibody-PE (8B50)
还可以产品编号 TMAY-02844P
Anti-GPRC5D Antibody-PE (8B50) 是一种 PE-conjugated Mouse 抗体，靶向 GPRC5D。Anti-GPRC5D Antibody-PE (8B50) 可用于 FCM。
Anti-GPRC5D Antibody-PE (8B50)
Anti-GPRC5D Antibody-PE (8B50)
还可以产品编号 TMAY-02844P
Anti-GPRC5D Antibody-PE (8B50) 是一种 PE-conjugated Mouse 抗体，靶向 GPRC5D。Anti-GPRC5D Antibody-PE (8B50) 可用于 FCM。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-GPRC5D Antibody-PE (8B50) is a PE-conjugated Mouse antibody targeting GPRC5D. Anti-GPRC5D Antibody-PE (8B50) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG2b |
| 克隆号 | 8B50 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human GPRC5D expression on CHO-K1 Cells were stained with PE-conjugated anti-Human GPRC5D. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 5 μL/Test, 0.1 mg/mL |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GPRC5D. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography, and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target antigen for MM-specific T cell-engaging therapies such as bispecific antibodies and CAR-T cells. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC/FITC |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human GPRC5D Protein |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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