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Anti-CD3 epsilon/CD3e Antibody (8Z76)

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产品编号 TMAC-00690
别名 TCRE, T3E, IMD18, CD3e molecule, ε (CD3-TCR complex), CD3e molecule, epsilon (CD3-TCR complex), CD3 ε/CD3e, CD3 ε, CD3 epsilon

Anti-CD3 epsilon/CD3e Antibody (8Z76) 是一种 Rabbit 抗体,靶向 CD3 epsilon/CD3e。Anti-CD3 epsilon/CD3e Antibody (8Z76) 可用于 FCM,IHC,IP,WB。

Anti-CD3 epsilon/CD3e Antibody (8Z76)

Anti-CD3 epsilon/CD3e Antibody (8Z76)

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产品编号 TMAC-00690 别名 TCRE, T3E, IMD18, CD3e molecule, ε (CD3-TCR complex), CD3e molecule, epsilon (CD3-TCR complex), CD3 ε/CD3e, CD3 ε, CD3 epsilon

Anti-CD3 epsilon/CD3e Antibody (8Z76) 是一种 Rabbit 抗体,靶向 CD3 epsilon/CD3e。Anti-CD3 epsilon/CD3e Antibody (8Z76) 可用于 FCM,IHC,IP,WB。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD3 epsilon/CD3e Antibody (8Z76) is a Rabbit antibody targeting CD3 epsilon/CD3e. Anti-CD3 epsilon/CD3e Antibody (8Z76) can be used in FCM,IHC,IP,WB.
别名TCRE, T3E, IMD18, CD3e molecule, ε (CD3-TCR complex), CD3e molecule, epsilon (CD3-TCR complex), CD3 ε/CD3e, CD3 ε, CD3 epsilon
Ig Type
IgG
克隆号
8Z76
交叉反应
Human
验证活性
1. Western blot analysis of CD3 epsilon on different lysates using anti-CD3 epsilon antibody at 1/1,000 dilution. Positive control: Lane 1: Jurkat, Lane 2: Human thymus.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD3 epsilon antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD3 epsilon antibody. Counter stained with hematoxylin.
4. Flow cytometric analysis of Jurkat cells with CD3 epsilon antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
应用FCMIHCIPWB
推荐剂量
WB: 1:1000-2000; IHC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The T cell antigen receptor (TCR) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. Much of this signaling process can be attributed to a multisubunit complex of proteins that associates directly with the TCR. This complex has been designated CD3 (cluster of differentiation 3). CD3 is composed of four polypeptides: ζ, γ, ε and δ. Each of these polypeptides contains at least one immunoreceptor tyrosine-based activation motif (ITAM). Engagement of TCR complex with foreign antigens induces tyrosine phosphorylation in the ITAM motifs and phosphorylated ITAMs function as docking sites for signaling molecules such as ZAP-70 and p85 subunit of PI-3 kinase. TCR ligation also induces a conformational change in CD3ε, such that a proline region is exposed and then associates with the adaptor protein Nck.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 23 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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