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Anti-HOOK2 Antibody (2W26)

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货号 TMAB-07236

Anti-HOOK2 Antibody (2W26) 是一种 Rabbit 抗体,靶向 HOOK2。Anti-HOOK2 Antibody (2W26) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-HOOK2 Antibody (2W26)

Anti-HOOK2 Antibody (2W26)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07236

Anti-HOOK2 Antibody (2W26) 是一种 Rabbit 抗体,靶向 HOOK2。Anti-HOOK2 Antibody (2W26) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍


生物活性
产品描述
Anti-HOOK2 Antibody (2W26) is a Rabbit antibody targeting HOOK2. Anti-HOOK2 Antibody (2W26) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
2W26
反应种属
Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IF: 1:100-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic. Note=Associates with discrete punctate structure that correspond to neither early or late endosomes, lysosomes, multivesicular bodies (MVBs), Golgi complex, endoplasmic reticulum, nor mitochondria.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Contributes to the establishment and maintenance of centrosome function. May function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell.
抗原信息
免疫原
A synthesized peptide: human HOOK2
抗原种属
Human
基因名称
HOOK2
基因ID
蛋白名称
Protein Hook homolog 2
Uniprot ID
功能
HOOK2 is a member of the Hook protein family. Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. HOOK2 localizes to the centrosome through all phases of the cell cycle. Interference with HOOK2 function results in the loss of the radial organization of microtubules suggesting that HOOK2 contributes to the establishment and maintenance of centrosomal structure and function. HOOK2 may contribute to the establishment and maintenance of the pericentrosomal localization of aggresomes by promoting the microtubule-based delivery of protein aggregates to pericentriolar aggresomes.
化学信息
分子量Theoretical: 83 kDa. Actual: 85 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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