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Anti-Dystonin Antibody (7U677)

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产品编号 TMAH-00369

Anti-Dystonin Antibody (7U677) 是一种 Mouse 抗体,靶向 Dystonin。Anti-Dystonin Antibody (7U677) 可用于 ELISA。

Anti-Dystonin Antibody (7U677)

Anti-Dystonin Antibody (7U677)

Rating icon 还可以
产品编号 TMAH-00369

Anti-Dystonin Antibody (7U677) 是一种 Mouse 抗体,靶向 Dystonin。Anti-Dystonin Antibody (7U677) 可用于 ELISA。

规格价格库存数量
50 μg
¥ 1,315
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100 μg
¥ 2,185
5日内发货
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产品介绍

生物活性
产品描述
Anti-Dystonin Antibody (7U677) is a Mouse antibody targeting Dystonin. Anti-Dystonin Antibody (7U677) can be used in ELISA.
Ig Type
IgG1
克隆号
7U677
交叉反应
Human
应用
ELISA
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Cell projection, axon.; [Isoform 1]: Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, myofibril, sarcomere, H zone.; [Isoform 2]: Cytoplasm, cytoskeleton.; [Isoform 3]: Cytoplasm, cytoskeleton. Cell junction, hemidesmosome.; [Isoform 6]: Nucleus. Nucleus envelope. Membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber.; [Isoform 7]: Cytoplasm, cytoskeleton. Cell projection, axon. Membrane. Note=Associates with axonal microtubules and intermediate filaments, but not with actin cytoskeleton, in sensory neurons.; [Isoform 8]: Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cell membrane; Lipid-anchor.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
纯度>95%
研究背景Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. Mediates docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport through its interaction with TMEM108 and DCTN1. plays a structural role in the assembly of hemidesmosomes of epithelial cells; anchors keratin-containing intermediate filaments to the inner plaque of hemidesmosomes. Required for the regulation of keratinocyte polarity and motility; mediates integrin ITGB4 regulation of RAC1 activity. required for bundling actin filaments around the nucleus. regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: DST Protein
抗原种属
Human
基因ID
667
Uniprot ID
研究领域
Signal Transduction
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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