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Anti-Dystonin Antibody (7U677) 是一种 Mouse 抗体,靶向 Dystonin。Anti-Dystonin Antibody (7U677) 可用于 ELISA。
Anti-Dystonin Antibody (7U677) 是一种 Mouse 抗体,靶向 Dystonin。Anti-Dystonin Antibody (7U677) 可用于 ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μg | ¥ 1,315 | 5日内发货 | |
100 μg | ¥ 2,185 | 5日内发货 |
产品描述 | Anti-Dystonin Antibody (7U677) is a Mouse antibody targeting Dystonin. Anti-Dystonin Antibody (7U677) can be used in ELISA. |
Ig Type | IgG1 |
克隆号 | 7U677 |
交叉反应 | Human |
应用 | ELISA |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
亚细胞定位 | Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Cell projection, axon.; [Isoform 1]: Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, myofibril, sarcomere, H zone.; [Isoform 2]: Cytoplasm, cytoskeleton.; [Isoform 3]: Cytoplasm, cytoskeleton. Cell junction, hemidesmosome.; [Isoform 6]: Nucleus. Nucleus envelope. Membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber.; [Isoform 7]: Cytoplasm, cytoskeleton. Cell projection, axon. Membrane. Note=Associates with axonal microtubules and intermediate filaments, but not with actin cytoskeleton, in sensory neurons.; [Isoform 8]: Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cell membrane; Lipid-anchor. |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | Protein G purified |
性状 | Liquid |
缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
纯度 | >95% |
研究背景 | Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. Mediates docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport through its interaction with TMEM108 and DCTN1. plays a structural role in the assembly of hemidesmosomes of epithelial cells; anchors keratin-containing intermediate filaments to the inner plaque of hemidesmosomes. Required for the regulation of keratinocyte polarity and motility; mediates integrin ITGB4 regulation of RAC1 activity. required for bundling actin filaments around the nucleus. regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein: DST Protein |
抗原种属 | Human |
基因ID | 667 |
Uniprot ID | |
研究领域 | Signal Transduction |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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