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Anti-FBXO45 Polyclonal Antibody
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产品编号 TMAB-00663
Anti-FBXO45 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FBXO45。Anti-FBXO45 Polyclonal Antibody 可用于 WB。
Anti-FBXO45 Polyclonal Antibody
Anti-FBXO45 Polyclonal Antibody
还可以产品编号 TMAB-00663
Anti-FBXO45 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FBXO45。Anti-FBXO45 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-FBXO45 Polyclonal Antibody is a Rabbit antibody targeting FBXO45. Anti-FBXO45 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Sample: Intestine (Mouse) Lysate at 40 μg Primary: Anti-FBXO45 (TMAB-00663) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kDa Observed band size: 31 kDa 2. Sample: Lane 1: Human A431 cell lysates Lane 2: Human MCF-7 cell lysates Lane 3: Human U251 cell lysates Lane 4: Human K562 cell lysates Lane 5: Human Jurkat cell lysates Primary: Anti-FBXO45 (TMAB-00663) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kDa Observed band size: 30 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell junction > synapse > postsynaptic cell membrane. Cell junction > synapse > presynaptic cell membrane. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | Belonging to the F-box family of proteins, FBXO45 is a 286 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO45 can directly interact with Skp1 p19 and CUL-1. FBXO45 has been shown to be an estrogen-induced gene. |
| 免疫原 | KLH conjugated synthetic peptide: human FBXO45 |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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