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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Insulin Receptor R Polyclonal Antibody

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货号 TMAB-07730

Anti-Insulin Receptor R Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Insulin Receptor R。Anti-Insulin Receptor R Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Insulin Receptor R Polyclonal Antibody

Anti-Insulin Receptor R Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07730

Anti-Insulin Receptor R Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Insulin Receptor R。Anti-Insulin Receptor R Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Insulin Receptor R Polyclonal Antibody is a Rabbit antibody targeting Insulin Receptor R. Anti-Insulin Receptor R Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor composed of two alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Member of the insulin RTK family, IRR shares high homology with the insulin (IR) and the insulin-like growth factor-1 receptor (IGF-1R), but doesn’t bind any of IR and IGF-1R known ligands. In contrast to the widespread patterns of expression to IR and IGF-1R, IRR demonstrates a very restricted cellular distribution in a subset of tissues of neuronal origin and its biological functions are still unknown.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Insulin receptor-related protein beta chain
抗原种属
Human
基因名称
INSRR
基因ID
3645
蛋白名称
Insulin receptor-related protein
Uniprot ID
P14616
功能
Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
化学信息
分子量Theoretical: 129 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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