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Anti-MICB Antibody (1F810) 是一种 Rabbit 抗体,靶向 MICB。Anti-MICB Antibody (1F810) 可用于 ELISA。
Anti-MICB Antibody (1F810) 是一种 Rabbit 抗体,靶向 MICB。Anti-MICB Antibody (1F810) 可用于 ELISA。
产品描述 | Anti-MICB Antibody (1F810) is a Rabbit antibody targeting MICB. Anti-MICB Antibody (1F810) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 1F810 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human MICB (rh MICB; TMPY-01066; NP_005922.2; Met 1-Gly 298). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | MHC class I polypeptide-related sequence B, also known as MICB, is a heavily glycosylated protein serving as a ligand for the type II receptor NKG2D. MICB shares 85% amino acid identity with MICA, a closely related protein, both of which contain three extracellular immunoglobulin-like domains, but without the capacity to bind peptide or interact with beta-2-microglobulin. acting as a stress-induced self-antigen, binding of MICB to the NKG2D receptor activates the cytolytic response of natural killer (NK) cells, CD8+αβ T cells, and γδ T cells on which the receptor is expressed. MICA/B is minimally expressed on normal cells, but are frequently expressed on epithelial tumors and can be induced by bacterial and viral infections. MICA/B recognition thus is involved in tumor surveillance, viral infections, and autoimmune diseases. |
偶联 | Unconjugated |
免疫原 | Recombinant Human MICB protein (TMPY-01066) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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