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Anti-STAT5A Antibody (6E796)
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产品编号 TMAC-03884
别名 Transcription factor STAT5B, Transcription factor STAT5A, STAT5B, STAT5, STAT 5B, STAT 5A, STA5A_HUMAN, Signal Transducer and Activator of Transcription 5B, Signal transducer and activator of transcription 5A, MGF
Anti-STAT5A Antibody (6E796) 是一种 Rabbit 抗体，靶向 STAT5A。Anti-STAT5A Antibody (6E796) 可用于 WB,ICC/IF,IHC,IP,FCM。
Anti-STAT5A Antibody (6E796)
Anti-STAT5A Antibody (6E796)
还可以产品编号 TMAC-03884 别名 Transcription factor STAT5B, Transcription factor STAT5A, STAT5B, STAT5, STAT 5B, STAT 5A, STA5A_HUMAN, Signal Transducer and Activator of Transcription 5B, Signal transducer and activator of transcription 5A, MGF
Anti-STAT5A Antibody (6E796) 是一种 Rabbit 抗体，靶向 STAT5A。Anti-STAT5A Antibody (6E796) 可用于 WB,ICC/IF,IHC,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,495 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-STAT5A Antibody (6E796) is a Rabbit antibody targeting STAT5A. Anti-STAT5A Antibody (6E796) can be used in WB,ICC/IF,IHC,IP,FCM. |
| 别名 | Transcription factor STAT5B, Transcription factor STAT5A, STAT5B, STAT5, STAT 5B, STAT 5A, STA5A_HUMAN, Signal Transducer and Activator of Transcription 5B, Signal transducer and activator of transcription 5A, MGF |
| Ig Type | IgG |
| 克隆号 | 6E796 |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of STAT5a on different lysates using anti-STAT5a antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: K562. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-STAT5a antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-STAT5a antibody. Counter stained with hematoxylin. 4. ICC staining STAT5a in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining STAT5a in C2C12 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. Flow cytometric analysis of Jurkat cells with STAT5a antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Signal transducer and activator of transcription 5A (Stat5a) and Stat5b, which share 96% homology, undergo receptor tyrosine kinase or G protein-coupled receptor-dependent phosphorylation in response to cytokines or growth factors, and then form homo- or heterodimers that translocate to the nucleus, where they initiate transcription. Activation of Stat5a via IL-2, IL-3, IL-7/ GM-CSF, erythropoietin, thrombopoietin and growth hormones influences proliferation, differentiation and apoptosis in lymphohematopoietic cells. Phos-phorylation of Stat5a at Ser127/Ser128 and Ser779 are contigent on ErbB-4-mediated activation of Stat5a. Activation of Stat5b via IL-2, IL-4, CSF-1 and growth hormones influences TCR signaling, apoptosis, adult mammary gland development and sexual dimorphism of liver gene expression. Stat5b is the major liver-expressed Stat5 form that has been shown to fuse with the retin-oic acid receptor a gene in acute promyelocytic leukemias (APLL). Stat5a/b null mice have severely impaired lymphoid development and differentiation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 92 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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