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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-Tissue Factor Antibody (5B269)

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货号 TMAY-03830

别名 TFA, TF, coagulation factor III (thromboplastin, tissue factor), coagulation factor III, coagulation factor 3, CD142

Anti-Tissue Factor Antibody (5B269) 是一种 Mouse 抗体，靶向 Tissue Factor。Anti-Tissue Factor Antibody (5B269) 可用于 ELISA(Cap)。

Anti-Tissue Factor Antibody (5B269)

Anti-Tissue Factor Antibody (5B269)

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货号 TMAY-03830 别名 TFA, TF, coagulation factor III (thromboplastin, tissue factor), coagulation factor III, coagulation factor 3, CD142

Anti-Tissue Factor Antibody (5B269) 是一种 Mouse 抗体，靶向 Tissue Factor。Anti-Tissue Factor Antibody (5B269) 可用于 ELISA(Cap)。

规格价格库存数量
20 μL
¥ 590
5日内发货
100 μL
¥ 1,684
5日内发货
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产品介绍

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产品描述
Anti-Tissue Factor Antibody (5B269) is a Mouse antibody targeting Tissue Factor. Anti-Tissue Factor Antibody (5B269) can be used in ELISA(Cap).
别名TFA, TF, coagulation factor III (thromboplastin, tissue factor), coagulation factor III, coagulation factor 3, CD142
Ig Type
Mouse IgG1
克隆号
5B269
反应种属
Rat
特异性
Rat Tissue Factor
应用ELISA(Cap)
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat Coagulation Factor III / Tissue Factor / CD142 (rR Coagulation Factor III / Tissue Factor / CD142; TMPY-03209; Q66HI4; Met1-Glu252). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemostatic and inflammatory processes. Activated monocytes present in the liver increase expression of tissue factor, and while accumulating in the organ they can intensify inflammation. Tissue factor is the protein that activates the blood clotting system by binding to, and activating, the plasma serine protease, factor VIIa, following vascular injury. Tissue factor is not only the main physiological initiator of normal blood coagulation, but is also important in the natural history of solid malignancies in that it potentiates metastasis and angiogenesis and mediates outside-in signalling. Tissue factor is expressed constitutively by many tissues which are not in contact with blood and by other cells upon injury or activation; the latter include endothelial cells, tissue macrophages, and peripheral blood monocytes. Coagulation Factor III is a transmembrane glycoprotein that localizes the coagulation serine protease factor VII/VIIa (FVII/VIIa) to the cell surface. The primary function of TF is to activate the clotting cascade. The TF:FVIIa complex also activates cells by cleavage of a G-protein coupled receptor called protease-activated receptor 2 (PAR2). TF is expressed by tumor cells and contributes to a variety of pathologic processes, such as thrombosis, metastasis, tumor growth, and tumor angiogenesis. As a key regulator of haemostasis and angiogenesis, it is also involved in the pathology of several diseases, including cardiovascular, inflammatory and neoplastic conditions.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Rat Coagulation Factor III / Tissue Factor / CD142 Protein (TMPY-03209)
抗原种属
Rat
研究领域
Serine Proteases and Regulators
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

thromboplastin, tissue factorCD-142CD 142
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