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IGFBP-3 Protein, Human, Recombinant (His) V2

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货号 TMPY-00835U

别名 insulin-like growth factor binding protein 3, IGFBP3, IBP3, BP-53

IGFBP-3 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is AAH18962.

IGFBP-3 Protein, Human, Recombinant (His) V2
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IGFBP-3 Protein, Human, Recombinant (His) V2

一键复制产品信息
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SPR兼容缓冲液
货号 TMPY-00835U 别名 insulin-like growth factor binding protein 3, IGFBP3, IBP3, BP-53

IGFBP-3 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is AAH18962.

规格价格库存数量
5 μg
¥ 496
现货
10 μg
¥ 791
现货
20 μg
¥ 1,330
现货
50 μg
¥ 2,650
3日内发货
100 μg
¥ 4,470
现货
200 μg
¥ 7,300
5日内发货
500 μg
¥ 13,900
5日内发货
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纯度: > 95% as determined by Bis-Tris PAGE
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产品介绍


生物活性
产品描述
IGFBP-3 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is AAH18962.
生物活性
Immobilized Human IGFBP-3, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human IGF-II, hFc Tag with the EC50 of 0.19 μg/ml determined by ELISA (QC Test).
Human IGFBP-3, His Tag captured on CM5 Chip via anti-his antibody can bind Human IGFI, hFc Tag with an affinity constant of 2.32 nM as determined in SPR assay (Biacore T200).
研究背景
Insulin-like growth factor binding protein-3 (IGFBP-3) is a p53 tumor suppressor-regulated protein and a major carrier for IGFs in circulation. Among six high-affinity IGFBPs, which are IGFBP-1 through 6, IGFBP-3 is the most extensively investigated IGFBP species with respect to its IGF/IGF-I receptor (IGF-IR)-independent biological actions beyond its endocrine/paracrine/autocrine role in modulating IGF action in cancer.
种属
Human
表达系统
HEK293 Cells
标签C-His
蛋白编号AAH18962
蛋白构建Gly28-Lys291
蛋白纯度
> 95% as determined by Tris-Bis PAGE
蛋白性状Lyophilized powder
缓冲液Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名insulin-like growth factor binding protein 3, IGFBP3, IBP3, BP-53
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量29.8 kDa (Predicted); 45-60 kDa (Due to glycosylation)
颜色White
物理性状Lyophilized powder
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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剂量转换

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技术支持

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