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Anti-Epac1 Antibody (3T871)
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产品编号 TMAC-01303
别名 RAPGEF3, Rap1 guanine nucleotide exchange factor directly activated by cAMP, RAP guanine nucleotide exchange factor 3, Rap guanine nucleotide exchange factor (GEF) 3, RAP guanine nucleotide exchange factor, MGC21410, Exchange protein directly activated by cAMP 1, Exchange factor directly activated by cAMP 1, EPAC1, Epac 1, EPAC, EPA1, CGEF1, CGEF 1, CAMPGEFI, cAMP regulated guanine nucleotide exchange factor I, CAMP GEFI, bcm910
Anti-Epac1 Antibody (3T871) 是一种 Rabbit 抗体，靶向 Epac1。Anti-Epac1 Antibody (3T871) 可用于 WB,IHC,IP,ICC/IF。
Anti-Epac1 Antibody (3T871)
Anti-Epac1 Antibody (3T871)
还可以产品编号 TMAC-01303 别名 RAPGEF3, Rap1 guanine nucleotide exchange factor directly activated by cAMP, RAP guanine nucleotide exchange factor 3, Rap guanine nucleotide exchange factor (GEF) 3, RAP guanine nucleotide exchange factor, MGC21410, Exchange protein directly activated by cAMP 1, Exchange factor directly activated by cAMP 1, EPAC1, Epac 1, EPAC, EPA1, CGEF1, CGEF 1, CAMPGEFI, cAMP regulated guanine nucleotide exchange factor I, CAMP GEFI, bcm910
Anti-Epac1 Antibody (3T871) 是一种 Rabbit 抗体，靶向 Epac1。Anti-Epac1 Antibody (3T871) 可用于 WB,IHC,IP,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Epac1 Antibody (3T871) is a Rabbit antibody targeting Epac1. Anti-Epac1 Antibody (3T871) can be used in WB,IHC,IP,ICC/IF. |
| 别名 | RAPGEF3, Rap1 guanine nucleotide exchange factor directly activated by cAMP, RAP guanine nucleotide exchange factor 3, Rap guanine nucleotide exchange factor (GEF) 3, RAP guanine nucleotide exchange factor, MGC21410, Exchange protein directly activated by cAMP 1, Exchange factor directly activated by cAMP 1, EPAC1, Epac 1, EPAC, EPA1, CGEF1, CGEF 1, CAMPGEFI, cAMP regulated guanine nucleotide exchange factor I, CAMP GEFI, bcm910 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse |
| 验证活性 | 1. Western blot analysis of Epac1 on mouse kidney tissue lysate using anti-Epac1 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-Epac1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue using anti-Epac1 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Epac1 antibody. Counter stained with hematoxylin. |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:10-50; IP: 1:10-50 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | 3',5' cyclic adenosine monophosphate (cAMP)-regulated guanine nucleotide exchange factors Epac (Epac1, cAMP-GEFI) and Epac2 (cAMP-GEFII) activate the Ras family GTPases Rap 1 and Rap 2 by promoting GTP binding in a cAMP-dependent manner. Eukaryotic cAMP is a second messenger that induces physiological responses such as gene expression, growth, differentiation, secretion and neurotransmission. The human Epac gene maps to chromosome 12q13.11 with transcript being abundant in the kidney and heart. In situ hybridization indicates expression of Epac in adult rat brain and selective expression in neonatal brain, including septum and thalamus. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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