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Anti-CD69 Antibody (9F511)

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Anti-CD69 Antibody (9F511)
产品编号 TMAY-01705
别名 VEA, CD69 molecule, AIM, AI452015, 5830438K24Rik

Anti-CD69 Antibody (9F511) 是一种 Mouse 抗体，靶向 CD69。Anti-CD69 Antibody (9F511) 可用于 FCM。

Anti-CD69 Antibody (9F511)
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Anti-CD69 Antibody (9F511)

Rating icon 还可以
Anti-CD69 Antibody (9F511)
产品编号 TMAY-01705 别名 VEA, CD69 molecule, AIM, AI452015, 5830438K24Rik

Anti-CD69 Antibody (9F511) 是一种 Mouse 抗体，靶向 CD69。Anti-CD69 Antibody (9F511) 可用于 FCM。

规格价格库存数量
100 μL
¥ 1,694
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD69 Antibody (9F511) is a Mouse antibody targeting CD69. Anti-CD69 Antibody (9F511) can be used in FCM.
别名VEA, CD69 molecule, AIM, AI452015, 5830438K24Rik
Ig Type
Mouse IgG1
克隆号
9F511
交叉反应
Human
验证活性
Flow cytometric analysis of Human CD69 expression on PHA-activated human whole blood Lymphocytes. Cells were stained with purified anti-Human CD69, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable Lymphocytes.
应用
FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD69 (rh CD69; TMPY-01234; NP_001772.1; Ser62-Lys199). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0
研究背景Early activation antigen CD69, also known as activation inducer molecule (AIM), is a single-pass type II membrane protein. Recently, cDNA clones encoding human and mouse CD69 were isolated and showed CD69 to be a member of the C-type lectin superfamily. It is one of the earliest cell surface antigens expressed by T cells following activation. Once expressed, CD69 acts as a costimulatory molecule for T cell activation and proliferation. In addition to mature T cells, CD69 is inducibly expressed by immature thymocytes, B cells, natural killer (NK) cells, monocytes, neutrophils and eosinophils, and is constitutively expressed by mature thymocytes and platelets. CD69 is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. The structure, chromosomal localization, expression and function of CD69 suggest that it is likely a pleiotropic immune regulator , potentially important in the activation and differentiation of a wide variety of hematopoietic cells. This membrane molecule transiently expresses on activated lymphocytes, and its selective expression in inflammatory infiltrates suggests that it plays a role in the pathogenesis of inflammatory diseases. CD69 plays a crucial role in the pathogenesis of allergen-induced eosinophilic airway inflammation and hyperresponsiveness and that CD69 could be a possible therapeutic target for asthmatic patients.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
APC/PerCP/FITC/PE
可提供抗体种类
5
抗原信息
免疫原
Recombinant Protein: Human CD69 Protein (TMPY-01234)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

AI-452015AI 452015

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