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Anti-CD69 Antibody (9F511)
还可以产品编号 TMAY-01705
Anti-CD69 Antibody (9F511) 是一种 Mouse 抗体，靶向 CD69。Anti-CD69 Antibody (9F511) 可用于 FCM。
Anti-CD69 Antibody (9F511)
Anti-CD69 Antibody (9F511)
还可以产品编号 TMAY-01705
Anti-CD69 Antibody (9F511) 是一种 Mouse 抗体，靶向 CD69。Anti-CD69 Antibody (9F511) 可用于 FCM。
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偶联与修饰
抗原信息
| 产品描述 | Anti-CD69 Antibody (9F511) is a Mouse antibody targeting CD69. Anti-CD69 Antibody (9F511) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 9F511 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human CD69 expression on PHA-activated human whole blood Lymphocytes. Cells were stained with purified anti-Human CD69, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable Lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD69 (rh CD69; TMPY-01234; NP_001772.1; Ser62-Lys199). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0 |
| 研究背景 | Early activation antigen CD69, also known as activation inducer molecule (AIM), is a single-pass type II membrane protein. Recently, cDNA clones encoding human and mouse CD69 were isolated and showed CD69 to be a member of the C-type lectin superfamily. It is one of the earliest cell surface antigens expressed by T cells following activation. Once expressed, CD69 acts as a costimulatory molecule for T cell activation and proliferation. In addition to mature T cells, CD69 is inducibly expressed by immature thymocytes, B cells, natural killer (NK) cells, monocytes, neutrophils and eosinophils, and is constitutively expressed by mature thymocytes and platelets. CD69 is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. The structure, chromosomal localization, expression and function of CD69 suggest that it is likely a pleiotropic immune regulator , potentially important in the activation and differentiation of a wide variety of hematopoietic cells. This membrane molecule transiently expresses on activated lymphocytes, and its selective expression in inflammatory infiltrates suggests that it plays a role in the pathogenesis of inflammatory diseases. CD69 plays a crucial role in the pathogenesis of allergen-induced eosinophilic airway inflammation and hyperresponsiveness and that CD69 could be a possible therapeutic target for asthmatic patients. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | APC/PerCP/FITC/PE |
| 可提供抗体种类 | 5 |
| 免疫原 | Recombinant Human CD69 Protein (TMPY-01234) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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