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Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841)

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产品编号 TMAY-02808P

Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841) 是一种 PE-conjugated Mouse 抗体,靶向 LILRB1/CD85j/ILT2。Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841) 可用于 FCM。

Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841)

Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841)

Rating icon 还可以
产品编号 TMAY-02808P

Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841) 是一种 PE-conjugated Mouse 抗体,靶向 LILRB1/CD85j/ILT2。Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841) 可用于 FCM。

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产品介绍

生物活性
产品描述
Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841) is a PE-conjugated Mouse antibody targeting LILRB1/CD85j/ILT2. Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841) can be used in FCM.
Ig Type
Monoclonal Mouse IgG1
克隆号
5D841
交叉反应
Human
验证活性
Flow cytometric analysis of Human LILRB1(CD85j) expression on human peripheral blood monocytes. Cells were stained with PE-conjugated Mouse anti-Human LILRB1(CD85j). The histogram were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
应用
FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD85 / ILT2 / ILR1 (rh CD85 / ILT2 / ILR1; TMPY-03995; ADJ55949.1; Met1-His458) and conjugated with PE under optimum conditions, the unreacted PE was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景LILRB1 (Leukocyte Immunoglobulin Like Receptor B1) is a Protein Coding gene. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). LILRB1 is encoded within the leukocyte receptor complex on 19q13.4, previously implicated to be a susceptibility region to systemic lupus erythematosus (SLE). LILRB1 binds to a wide range of Major Histocompatibility Complex Class I molecules (MHCIs) and transduces negative signals that can, for example, prevent the killing of MHCI-expressing cells. LILRB1 transcription is correlated with surface protein expression on NK cells. Diseases associated with LILRB1 include Alzheimer's Disease 12 and Severe Pre-Eclampsia.
偶联与修饰
偶联
PE
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
Recombinant Human CD85 / ILT2 / ILR1 protein (TMPY-03995)
抗原种属
Human
研究领域
ITIM/ITAM Immunoreceptors and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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