GRO gama/CXCL3 Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.3 kDa and the accession number is Q6W5C0.

Mouse

P. pastoris (Yeast)

GRO γ,Gm1960,Dcip1,chemokine (C-X-C motif) ligand 3

A DNA sequence encoding the mouse Cxcl3 (NP_976065.1) (Ala28-Ser100) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Ala 28

> 95 % as determined by SDS-PAGE.

A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.

It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

CXCL3 is involved in migration, invasion, proliferation and tubule formation of trophoblasts and may play a key role in the pathogenesis of preeclampsia. CXCL3 autocrine/paracrine pathways are involved in the development of prostate cancer by regulating the expression of the target genes that are related to the progression of malignancies. CXCL3 is a novel adipokine that facilitates adipogenesis in an autocrine and/or a paracrine manner through induction of c/ebpb and c/ebpd. CXCL3 and its receptor CXCR2 are overexpressed in prostate cancer cells, prostate epithelial cells and prostate cancer tissues, which may play multiple roles in prostate cancer progression and metastasis.