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Anti-Connexin 31.1 Polyclonal Antibody

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货号 TMAB-04560

Anti-Connexin 31.1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Connexin 31.1。Anti-Connexin 31.1 Polyclonal Antibody 可用于 WB。

Anti-Connexin 31.1 Polyclonal Antibody

Anti-Connexin 31.1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-04560

Anti-Connexin 31.1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Connexin 31.1。Anti-Connexin 31.1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Connexin 31.1 Polyclonal Antibody is a Rabbit antibody targeting Connexin 31.1. Anti-Connexin 31.1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Cell junction > gap junction.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The connexin family of proteins form hexameric complexes, called connexons, that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane ?helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino acid substitutions in the most highly conserved domains; the transmembrane and extracellular regions. Connexin 31.1, Cx31.1 or Gap junction beta-5 protein, is a 271 amino acid protein that is predominantly expressed in skin with lower expression in testis. Expression of connexin 31.1 is required for normal placental development in mice. Down-regulation of the connexin 31.1 gene correlates with head and neck squamous cell carcinomas (HNSCC) and therefore it may be a potential therapeutic target.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Connexin 31.1
抗原种属
Human
基因名称
GJB5
基因ID
2709
蛋白名称
Gap junction beta-5 protein
Uniprot ID
O95377
功能
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
化学信息
分子量Theoretical: 31 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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