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Anti-CD155/PVR Antibody-FITC (2B632)
还可以产品编号 TMAY-00277F
Anti-CD155/PVR Antibody-FITC (2B632) 是一种 FITC-conjugated Mouse 抗体，靶向 CD155/PVR。Anti-CD155/PVR Antibody-FITC (2B632) 可用于 FCM。
Anti-CD155/PVR Antibody-FITC (2B632)
Anti-CD155/PVR Antibody-FITC (2B632)
还可以产品编号 TMAY-00277F
Anti-CD155/PVR Antibody-FITC (2B632) 是一种 FITC-conjugated Mouse 抗体，靶向 CD155/PVR。Anti-CD155/PVR Antibody-FITC (2B632) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-CD155/PVR Antibody-FITC (2B632) is a FITC-conjugated Mouse antibody targeting CD155/PVR. Anti-CD155/PVR Antibody-FITC (2B632) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 2B632 |
| 交叉反应 | Human |
| 验证活性 | 1. Profile of CD155 reactivity on HeLa cells analyzed by flow cytometry. 2. Immunofluorescence staining of Human CD155 in A549 cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with Mouse anti-Human CD155 monoclonal antibody (FITC-conjugated, 10 µg/ml) at 4°C overnight, and counterstained with DAPI (blue). Positive staining was localized to plasma membrane. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD155 / PVR (rh CD155 / PVR; TMPY-01386; P15151-1; Met 1-Asn 343) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhesion, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/APC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human CD155 protein (TMPY-01386) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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