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Anti-FFAR3/GPR41 Polyclonal Antibody

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货号 TMAB-00667

别名 GPR41, gpcr41, G protein coupled receptor 41, Free fatty acid receptor 3, FFAR3, FFA3R

Anti-FFAR3/GPR41 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FFAR3/GPR41。Anti-FFAR3/GPR41 Polyclonal Antibody 可用于 ELISA,ICC/IF,IF,IHC-Fr,IHC-P。

Anti-FFAR3/GPR41 Polyclonal Antibody

Anti-FFAR3/GPR41 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-00667 别名 GPR41, gpcr41, G protein coupled receptor 41, Free fatty acid receptor 3, FFAR3, FFA3R

Anti-FFAR3/GPR41 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FFAR3/GPR41。Anti-FFAR3/GPR41 Polyclonal Antibody 可用于 ELISA,ICC/IF,IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-FFAR3/GPR41 Polyclonal Antibody is a Rabbit antibody targeting FFAR3/GPR41. Anti-FFAR3/GPR41 Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P.
别名GPR41, gpcr41, G protein coupled receptor 41, Free fatty acid receptor 3, FFAR3, FFA3R
Ig Type
IgG
反应种属
(predicted:Human)
应用ELISAICC/IFIFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane.
组织特异性Highest level in adipose tissue, and lower expression across all tissues tested.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. GPRs translate extracellular signals into intracellular signals (a process called G-protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR41 (G-protein coupled receptor 41), also known as FFAR3 (Free fatty acid receptor 3), is a 346 amino acid multi-pass membrane protein that belongs to the G protein-coupled receptor family. Expressed at high levels in adipose tissue and at lower levels throughout the body, GPR41 functions as a receptor for short chain fatty acids via elevation of intracellular calcium levels and inhibition of adenylyl cyclase.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FFAR3
抗原种属
Human
基因名称
FFAR3
基因ID
蛋白名称
Free fatty acid receptor 3
Uniprot ID
研究领域
Binding proteins,Fatty acids,Fatty acid oxidation
功能
Receptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5-trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.
化学信息
分子量Theoretical: 39 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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