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别名 GPR41, gpcr41, G protein coupled receptor 41, Free fatty acid receptor 3, FFAR3, FFA3R
Anti-FFAR3/GPR41 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FFAR3/GPR41。Anti-FFAR3/GPR41 Polyclonal Antibody 可用于 ELISA,ICC/IF,IF,IHC-Fr,IHC-P。
Anti-FFAR3/GPR41 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FFAR3/GPR41。Anti-FFAR3/GPR41 Polyclonal Antibody 可用于 ELISA,ICC/IF,IF,IHC-Fr,IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-FFAR3/GPR41 Polyclonal Antibody is a Rabbit antibody targeting FFAR3/GPR41. Anti-FFAR3/GPR41 Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P. |
| 别名 | GPR41, gpcr41, G protein coupled receptor 41, Free fatty acid receptor 3, FFAR3, FFA3R |
| Ig Type | IgG |
| 反应种属 | (predicted:Human) |
| 应用 | ELISAICC/IFIFIHC-FrIHC-P |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Highest level in adipose tissue, and lower expression across all tissues tested. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. GPRs translate extracellular signals into intracellular signals (a process called G-protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR41 (G-protein coupled receptor 41), also known as FFAR3 (Free fatty acid receptor 3), is a 346 amino acid multi-pass membrane protein that belongs to the G protein-coupled receptor family. Expressed at high levels in adipose tissue and at lower levels throughout the body, GPR41 functions as a receptor for short chain fatty acids via elevation of intracellular calcium levels and inhibition of adenylyl cyclase. |
| 免疫原 | KLH conjugated synthetic peptide: human FFAR3 |
| 抗原种属 | Human |
| 基因名称 | FFAR3 |
| 基因ID | |
| 蛋白名称 | Free fatty acid receptor 3 |
| Uniprot ID | |
| 研究领域 | Binding proteins,Fatty acids,Fatty acid oxidation |
| 功能 | Receptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5-trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate. |
| 分子量 | Theoretical: 39 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |