购物车
全部删除
您的购物车当前为空
Anti-SorLA Antibody (1G832) 是一种 Rabbit 抗体,靶向 SorLA。Anti-SorLA Antibody (1G832) 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-SorLA Antibody (1G832) 是一种 Rabbit 抗体,靶向 SorLA。Anti-SorLA Antibody (1G832) 可用于 WB,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 780 | 5日内发货 | |
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-SorLA Antibody (1G832) is a Rabbit antibody targeting SorLA. Anti-SorLA Antibody (1G832) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 克隆号 | 1G832 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBIHC-PIHC-FrIF |
| 推荐剂量 | WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IF: 1:100-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Expressed mainly in brain, where it is most abundant in the cerebellum, cerebral cortex and the occipital pole; low expression in the putamen and the thalamus. According to PubMed:9157966, found in spinal cord, testis, liver, kidney and pancreas with detectable levels in placenta, lung and heart. According to PubMed:8940146, expressed in the prostate, ovary, thyroid and spleen, but not found in kidney, liver, lung, skeletal muscle, bone marrow and adrenals. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Sorting receptor that directs several proteins to their correct location within the cell (Probable). Along with AP-1 complex, involved Golgi apparatus - endosome sorting.Sorting receptor for APP, regulating its intracellular trafficking and processing into amyloidogenic-beta peptides. Retains APP in the trans-Golgi network, hence preventing its transit through late endosomes where amyloid beta peptides Abeta40 and Abeta42 are generated. |
| 免疫原 | A synthesized peptide: human Sortilin related receptor |
| 抗原种属 | Human |
| 基因名称 | SORL1 |
| 基因ID | |
| 蛋白名称 | Sortilin-related receptor |
| Uniprot ID | |
| 功能 | Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. |
| 分子量 | Theoretical: 248 kDa. Actual: 270 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |