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Anti-PD-1 Antibody (6A192)

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Anti-PD-1 Antibody (6A192)
产品编号 TMAC-03106
别名 SLEB2, programmed cell death 1, PD-1, PD1, hSLE1, hPD-l, hPD-1, CD279

Anti-PD-1 Antibody (6A192) 是一种 Rabbit 抗体,靶向 PD-1。Anti-PD-1 Antibody (6A192) 可用于 WB,IHC。

Anti-PD-1 Antibody (6A192)

Anti-PD-1 Antibody (6A192)

Rating icon 还可以
Anti-PD-1 Antibody (6A192)
产品编号 TMAC-03106 别名 SLEB2, programmed cell death 1, PD-1, PD1, hSLE1, hPD-l, hPD-1, CD279

Anti-PD-1 Antibody (6A192) 是一种 Rabbit 抗体,靶向 PD-1。Anti-PD-1 Antibody (6A192) 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-PD-1 Antibody (6A192) is a Rabbit antibody targeting PD-1. Anti-PD-1 Antibody (6A192) can be used in WB,IHC.
别名SLEB2, programmed cell death 1, PD-1, PD1, hSLE1, hPD-l, hPD-1, CD279
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of over-expressed PD1 (whole extracellular domain) on 293T cell lysate using anti-PD1 antibody at 1/500 dilution.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PD1 antibody. Counter stained with hematoxylin.
应用
推荐剂量
WB: 1:500-1000; IHC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Pdcd-1 (Programmed Cell Death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. Pdcd-1 contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) within the cytoplasmic domain, which is conserved between the mouse and human homologs. Expression of Pdcd-1 is detected in mouse thymus, and it is induced in stimulated B and T cell lines, where it may play a role in the negative regulation of various immune responses. Receptors such as Pdcd-1 function by recruiting tyrosine phosphatases, including SHP-1 and SHIP, which are responsible for altering various B cell responses. Additionally, in activated lymphocytes, Pdcd-1 mediates the activation of the classical type of programmed cell death.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 32 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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