HNT/NTM Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.6 kDa and the accession number is Q9P121-1.
生物活性 | Testing in progress |
产品描述 | HNT/NTM Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.6 kDa and the accession number is Q9P121-1. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-hFc |
蛋白编号 | Q9P121-1 |
别名 | neurotrimin, NTRI, IGLON2, HNT |
蛋白构建 | The Human NTM (NP_057606.1) (Met1-Gly312) was expressed with the Fc region of Human IgG1 at the C-terminus. |
蛋白纯度 | > 95 % as determined by SDS-PAGE. |
分子量 | 57.6 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | NTM (Neurotrimin) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. IgLONs have been associated with psychiatric disorders, intelligence, body weight, heart disease, and tumors. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. Neurotrimin is a member of the family of neural cell adhesion molecules. Its expression pattern suggests that Ntm promotes axonal fasciculation, guides nerve fibers to specific targets and stabilizes synapses as it accumulates coincident with synaptogenesis. Diseases associated with NTM include Connective Tissue Disease and Jacobsen Syndrome. |
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HNT/NTM Protein, Human, Recombinant (hFc) neurotrimin NTRI IGLON 2 IGLON-2 IGLON2 HNT recombinant recombinant-proteins proteins protein