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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Capicua Polyclonal Antibody

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货号 TMAB-03608

Anti-Capicua Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Capicua。Anti-Capicua Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Capicua Polyclonal Antibody

Anti-Capicua Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-03608

Anti-Capicua Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Capicua。Anti-Capicua Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Capicua Polyclonal Antibody is a Rabbit antibody targeting Capicua. Anti-Capicua Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed in fetal brain.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Capicua is the mammalian ortholog of the drosophilia Cic gene and is part of the HMG-box protein superfamily. Expressed primarily in the fetal brain, Capicua functions as a transciptional repressor and is involved in the development of the nervous system through interaction with the ATXN1 protein. When ATXN1 assembles into stable complexes, it directly binds Capicua, thereby mediating both the activity and expression of Capicua. When Capicua is active, it is able to interact with other developmental proteins to restrict the growth of granule cells and regulate normal neuronal development. Disruptions in the the association of Capicua with proteins such as ATXN1 are thought to cause medulloblastoma, the most common form of perdiatric brain tumor arising from irregular growth of granule cells.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Capicua
抗原种属
Human
基因名称
CIC
基因ID
23152
蛋白名称
Protein capicua homolog
Uniprot ID
Q96RK0
功能
Transcriptional repressor which may play a role in development of the central nervous system (CNS).
化学信息
分子量Theoretical: 164 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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