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Anti-Dexras1 Polyclonal Antibody

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货号 TMAB-05107

Anti-Dexras1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Dexras1。Anti-Dexras1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Dexras1 Polyclonal Antibody

Anti-Dexras1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05107

Anti-Dexras1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Dexras1。Anti-Dexras1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-Dexras1 Polyclonal Antibody is a Rabbit antibody targeting Dexras1. Anti-Dexras1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Cytoplasm > perinuclear region. Nucleus.
组织特异性Expressed in a variety of tissues including heart, cardiovascular tissues, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, gastrointestinal and reproductive tissues.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2011]
抗原信息
免疫原
KLH conjugated synthetic peptide: human Dexras1
抗原种属
Human
基因名称
RASD1
基因ID
蛋白名称
Dexamethasone-induced Ras-related protein 1
Uniprot ID
功能
Small GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65.
化学信息
分子量Theoretical: 31 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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