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Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636) 是一种 Rabbit 抗体,靶向 Enterohemorrhagic E. coli (EHEC) stx2B。Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636) 可用于 ELISA。
Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636) 是一种 Rabbit 抗体,靶向 Enterohemorrhagic E. coli (EHEC) stx2B。Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636) 可用于 ELISA。
产品描述 | Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636) is a Rabbit antibody targeting Enterohemorrhagic E. coli (EHEC) stx2B. Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 6H636 |
交叉反应 | E. coli |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Enterohemorrhagic E. coli (EHEC) stx2B (TMPY-02447; Q93EY4; Met1-Asp89). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | E. Coli STX2B is a subunit of Stx2. Stx2, together with Stx1, formed a family of related toxins which are known as shiga toxins. Shiga toxins are mainly produced by the bacteria S. dysenteriae and the Shigatoxigenic group of Escherichia coli, which includes serotypes O157:H7, O104:H4, and other enterohemorrhagic E. coli (EHEC). A total of 3222 outbreak cases (including 39 deaths) have been reported in northern Germany in May through June 2011. The outbreak strain was typed as an enteroaggregative Shiga-toxin–producing E. coli O104:H4, producing extended-spectrum beta-lactamase. The toxin has two subunits—A and B. E. Coli STX2B is the B subunit. It is a pentamer that binds to specific glycolipids on the host cell, specifically globotriaosylceramide. Following this, the A subunit is internalised and cleaved into two parts. Stx2 has been found to be approximately 400 times more toxic (as quantified by LD50 in mice) than Stx-1. The Stx1 and Stx2 B subunits form a pentameric structure that binds to globotriaosylceramide receptors on eukaryotic cells and promotes endocytosis. |
偶联 | Unconjugated |
免疫原 | Recombinant Enterohemorrhagic E. coli (EHEC) stx2B Protein (TMPY-02447) |
抗原种属 | E. coli |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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