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Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636)

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产品编号 TMAY-02855

Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636) 是一种 Rabbit 抗体,靶向 Enterohemorrhagic E. coli (EHEC) stx2B。Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636) 可用于 ELISA。

Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636)

Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636)

Rating icon 还可以
产品编号 TMAY-02855

Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636) 是一种 Rabbit 抗体,靶向 Enterohemorrhagic E. coli (EHEC) stx2B。Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636) is a Rabbit antibody targeting Enterohemorrhagic E. coli (EHEC) stx2B. Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
6H636
交叉反应
E. coli
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Enterohemorrhagic E. coli (EHEC) stx2B (TMPY-02447; Q93EY4; Met1-Asp89).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景E. Coli STX2B is a subunit of Stx2. Stx2, together with Stx1, formed a family of related toxins which are known as shiga toxins. Shiga toxins are mainly produced by the bacteria S. dysenteriae and the Shigatoxigenic group of Escherichia coli, which includes serotypes O157:H7, O104:H4, and other enterohemorrhagic E. coli (EHEC). A total of 3222 outbreak cases (including 39 deaths) have been reported in northern Germany in May through June 2011. The outbreak strain was typed as an enteroaggregative Shiga-toxin–producing E. coli O104:H4, producing extended-spectrum beta-lactamase. The toxin has two subunits—A and B. E. Coli STX2B is the B subunit. It is a pentamer that binds to specific glycolipids on the host cell, specifically globotriaosylceramide. Following this, the A subunit is internalised and cleaved into two parts. Stx2 has been found to be approximately 400 times more toxic (as quantified by LD50 in mice) than Stx-1. The Stx1 and Stx2 B subunits form a pentameric structure that binds to globotriaosylceramide receptors on eukaryotic cells and promotes endocytosis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Enterohemorrhagic E. coli (EHEC) stx2B Protein (TMPY-02447)
抗原种属
E. coli
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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