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Anti-EGFR Antibody (1M293)

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货号 TMAY-00021

别名 PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor

Anti-EGFR Antibody (1M293) 是一种 Mouse 抗体,靶向 EGFR。Anti-EGFR Antibody (1M293) 可用于 ELISA。

Anti-EGFR Antibody (1M293)

Anti-EGFR Antibody (1M293)

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Rating icon 还可以
货号 TMAY-00021 别名 PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor

Anti-EGFR Antibody (1M293) 是一种 Mouse 抗体,靶向 EGFR。Anti-EGFR Antibody (1M293) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,684
5日内发货
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产品介绍


生物活性
产品描述
Anti-EGFR Antibody (1M293) is a Mouse antibody targeting EGFR. Anti-EGFR Antibody (1M293) can be used in ELISA.
别名PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor
Ig Type
Mouse IgG2b
克隆号
1M293
反应种属
Human
特异性
Human EGFR
No cross-reactivity in ELISA with
Human EGFR/ErbB1
Human ErbB2
Human ErbB3
Human ErbB4
Human cell lysate (293 cell line)
应用ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human EGFR / ErbB / HER1 (rh EGFR / ErbB / HER1; Catalog #10001-H08H; Met 1-Ser 645; NP_005219). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human EGFR / ErbB / HER1 Protein (TMPY-00742)
抗原种属
Human
研究领域
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.
存储-20°C for 1 year

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