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Anti-IL-1 beta Antibody (3E298)
还可以产品编号 TMAY-01258
Anti-IL-1 beta Antibody (3E298) 是一种 Mouse 抗体，靶向 IL-1 beta。Anti-IL-1 beta Antibody (3E298) 可用于 WB。
Anti-IL-1 beta Antibody (3E298)
Anti-IL-1 beta Antibody (3E298)
还可以产品编号 TMAY-01258
Anti-IL-1 beta Antibody (3E298) 是一种 Mouse 抗体，靶向 IL-1 beta。Anti-IL-1 beta Antibody (3E298) 可用于 WB。
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抗原信息
| 产品描述 | Anti-IL-1 beta Antibody (3E298) is a Mouse antibody targeting IL-1 beta. Anti-IL-1 beta Antibody (3E298) can be used in WB. |
| Ig Type | Monoclonal Mouse IgG2b |
| 克隆号 | 3E298 |
| 交叉反应 | Human |
| 验证活性 | Anti-IL-1 beta mouse monoclonal antibody at 1:500 dilution. -Lane A: Untreated THP1 Whole Cell Lysate. -Lane B: THP-1 cells differentiated with TPA(80 nM,overnight) followed by treatment with LPS(1 μg/ml ,8h). -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:31 kDa. -Observed band size: kDa |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of a successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide corresponding to the center region of the Human IL-1 beta |
| 抗原种属 | Human |
| 研究领域 | Neuroinflammation |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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