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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-Mcl1 (Ser159+Thr163) Polyclonal Antibody

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货号 TMAB-10956

Anti-Phospho-Mcl1 (Ser159+Thr163) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Mcl1 (Ser159+Thr163)。Anti-Phospho-Mcl1 (Ser159+Thr163) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-Phospho-Mcl1 (Ser159+Thr163) Polyclonal Antibody

Anti-Phospho-Mcl1 (Ser159+Thr163) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10956

Anti-Phospho-Mcl1 (Ser159+Thr163) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Mcl1 (Ser159+Thr163)。Anti-Phospho-Mcl1 (Ser159+Thr163) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Mcl1 (Ser159+Thr163) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Mcl1 (Ser159+Thr163). Anti-Phospho-Mcl1 (Ser159+Thr163) Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Dog,Cow,Horse)
应用IHC-PIHC-FrICC/IFIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass membrane protein (Potential). Cytoplasm. Mitochondrion. Nucleus, nucleoplasm. Note=Cytoplasmic, associated with mitochondria.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Mcl1 is an anti-apoptotic member of Bcl2 family originally isolated from the ML1 human myeloid leukemia cell line during phorbol ester-induced differentiation along the monocyte/macrophage pathway. Mcl1 localizes to the mitochondria, interacts with and antagonizes pro-apoptotic Bcl2 family members, and inhibits apoptosis by a number of cytotoxic stimuli. It is involved in programing of differentiation and concomitant maintenance of viability but not of proliferation. Isoform 1 inhibits apoptosis while isoform 2 promotes it. Expression increases early during phorbol-ester induced differentiation along the monocyte/macrophage pathway in myeloid leukemia cell lines ML1.
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human Mcl 1 around the phosphorylation site of Ser159/Thr163
抗原种属
Human
基因名称
MCL1
基因ID
4170
蛋白名称
Induced myeloid leukemia cell differentiation protein Mcl-1
Uniprot ID
Q07820
功能
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
化学信息
分子量Theoretical: 39 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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