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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-IKB alpha Antibody (3W985)

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货号 TMAB-07571

Anti-IKB alpha Antibody (3W985) 是一种 Rabbit 抗体，靶向 IKB alpha。Anti-IKB alpha Antibody (3W985) 可用于 IHC-P,ICC/IF,WB,IHC-Fr,IF。

Anti-IKB alpha Antibody (3W985)

Anti-IKB alpha Antibody (3W985)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07571

Anti-IKB alpha Antibody (3W985) 是一种 Rabbit 抗体，靶向 IKB alpha。Anti-IKB alpha Antibody (3W985) 可用于 IHC-P,ICC/IF,WB,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,495
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

生物活性
产品描述
Anti-IKB alpha Antibody (3W985) is a Rabbit antibody targeting IKB alpha. Anti-IKB alpha Antibody (3W985) can be used in IHC-P,ICC/IF,WB,IHC-Fr,IF.
Ig Type
IgG
克隆号
3W985
反应种属
Human,Mouse,Rat
应用IHC-PICC/IFWBIHC-FrIF
推荐剂量
IHC-P: 1:50-200; ICC/IF: 1:50-200; WB: 1:500-2000; IHC-Fr: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export.
组织特异性Highly expressed in lymph node, thymus followed by liver, brain, muscle, kidney, gastrointestinal and reproductive tract.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液PBS (pH7.2) with 40% Glycerol, 0.05% BSA and 0.02% Proclin300.
浓度1mg/ml
研究背景This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
抗原信息
免疫原
A synthesized peptide: human IkB alpha
抗原种属
Human
基因名称
NFKBIA
基因ID
4792
蛋白名称
NF-kappa-B inhibitor alpha
Uniprot ID
P25963
功能
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
化学信息
分子量Theoretical: 36 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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