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Anti-CST3 Antibody (6K312)
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产品编号 TMAC-01066
别名 γ-trace, Post-γ-globulin, Post-gamma-globulin, Neuroendocrine basic polypeptide, Gamma-trace, Cystatin-C, Cystatin-3, CST3
Anti-CST3 Antibody (6K312) 是一种 Rabbit 抗体，靶向 CST3。Anti-CST3 Antibody (6K312) 可用于 WB,IHC。
Anti-CST3 Antibody (6K312)
Anti-CST3 Antibody (6K312)
还可以产品编号 TMAC-01066 别名 γ-trace, Post-γ-globulin, Post-gamma-globulin, Neuroendocrine basic polypeptide, Gamma-trace, Cystatin-C, Cystatin-3, CST3
Anti-CST3 Antibody (6K312) 是一种 Rabbit 抗体，靶向 CST3。Anti-CST3 Antibody (6K312) 可用于 WB,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
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产品介绍
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抗原信息
化学信息
| 产品描述 | Anti-CST3 Antibody (6K312) is a Rabbit antibody targeting CST3. Anti-CST3 Antibody (6K312) can be used in WB,IHC. |
| 别名 | γ-trace, Post-γ-globulin, Post-gamma-globulin, Neuroendocrine basic polypeptide, Gamma-trace, Cystatin-C, Cystatin-3, CST3 |
| Ig Type | IgG |
| 克隆号 | 6K312 |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of Cystatin C on different lysates using anti-Cystatin C antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: Mouse spleen. 2. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Cystatin C antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Cystatin C antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Cystatin C antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse placenta tissue using anti-Cystatin C antibody. Counter stained with hematoxylin. 6. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Cystatin C antibody. Counter stained with hematoxylin. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Cystatin C is a cysteine (thiol) protease inhibitor that belongs to the type II cystatin gene superfamily and is the most abundant extracellular inhibitor of cysteine proteases. Cystatin C is a constitutively secreted, amyloidogenic protein, which forms a two-fold symmetric dimer and modulates both cysteine protease activity and the expression of class II MHC molecules. Expression of cystatin C is an indicator of kidney function and glomerular filtration rate. Mutations in the cystatin C gene can lead to protein aggregates, which are implicated in hereditary amyloid angiopathy (HCCAA) and cerebral hemorrhage. Although both wild-type and mutant cystatin C are capable of forming concentration dependent inactive dimers, mutant cystatin C dimerizes at lower concentrations and is more susceptible to serine proteases, which may facilitate aggregation. In neuronal cells, oxidative stress stimulates expression of cystatin C, which may positively regulate apoptosis. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 16 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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