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Anti-Phospho-MYPT1 (Thr696) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-MYPT1 (Thr696)。Anti-Phospho-MYPT1 (Thr696) Polyclonal Antibody 可用于 WB,IHC-P,ICC/IF,ELISA。
Anti-Phospho-MYPT1 (Thr696) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-MYPT1 (Thr696)。Anti-Phospho-MYPT1 (Thr696) Polyclonal Antibody 可用于 WB,IHC-P,ICC/IF,ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,240 | 5日内发货 |
产品描述 | Anti-Phospho-MYPT1 (Thr696) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MYPT1 (Thr696). Anti-Phospho-MYPT1 (Thr696) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA. |
别名 | p-MYPT1 (Thr696), p-MYPT1 (T696), MYPT1 (p-Thr696), MYPT1 (p-T696) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
应用 | |
推荐剂量 | IHC-P: 1:100-300; ICC/IF: 1:200-1000; ELISA: 1:10000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
性状 | Liquid |
缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
研究背景 | protein phosphatase 1 regulatory subunit 12A(PPP1R12A) Homo sapiens Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosph |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human MYPT1 around the phosphorylation site of Thr696. AA range:661-710 |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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