规格

价格

库存

数量

1 mg

¥ 313

现货

5 mg

¥ 727

现货

10 mg

¥ 1,290

现货

25 mg

¥ 2,620

现货

生物活性

产品描述	Gonadorelin Acetate (Luteinizing Hormone Releasing Hormone (LH-RH)) is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
体外活性	黄体生成激素释放激素(LH-RH)，亦称为促性腺激素释放激素(GnRH)，是大脑、脑垂体与性腺功能之间的主要联系，对脊椎动物的繁殖扮演关键角色。LH-RH及其类似物的内分泌作用是通过LHRH的高亲和力膜受体在脑垂体性腺细胞上介导的。LHRH及其受体在与激素相关的肿瘤中有表达，例如前列腺癌，充当局部自分泌/旁分泌的生长抑制因子。在前列腺癌细胞中，LHRH受体与Gi-cAMP途径相耦合，以抑制细胞增殖。
体内活性	促黄体生成激素释放激素(Luteinizing Hormone Releasing Hormone)治疗可使阴道开口时间提前5天，这被用作青春期开始时间的初步指标。
动物实验	Rat:Immature female Sprague-Dawley rats receive either 50 ng Luteinizing Hormone Releasing Hormone (LH-RH)/kg BW or 20 mg NMA/kg BW in a 10% dextrose, 0.9% NaCl solution, while controls receive only vehicle. After completion of the treatment, rats are examined daily for vaginal opening.
别名	醋酸戈那瑞林, Luteinizing Hormone Releasing Hormone (LH-RH), human, Luteinizing Hormone Releasing Hormone (LH-RH), Gonadorelin Acetate (33515-09-2 free base), Gonadorelin Acetate

化学信息

分子量	1302.39
分子式	C₅₉H₈₃N₁₇O₁₇
CAS No.	71447-49-9
Smiles	CC(O)=O.CC(O)=O.CC(C)CC(NC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CO)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1cnc[nH]1)NC(=O)C1CCC(=O)N1)C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NCC(N)=O
密度	no data available
Sequence	H-Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH₂
Sequence Short	XHWSYGLRPG

储存&溶解度

存储

Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

H2O: 250 mg/mL (191.95 mM), Sonication is recommended.

溶液配制表

H2O

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

Gonadorelin Acetate