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Anti-p53 Antibody (8U839)
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产品编号 TMAC-02990
Anti-p53 Antibody (8U839) 是一种 Rabbit 抗体，靶向 p53。Anti-p53 Antibody (8U839) 可用于 WB,ICC/IF。
Anti-p53 Antibody (8U839)
Anti-p53 Antibody (8U839)
还可以产品编号 TMAC-02990
Anti-p53 Antibody (8U839) 是一种 Rabbit 抗体，靶向 p53。Anti-p53 Antibody (8U839) 可用于 WB,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-p53 Antibody (8U839) is a Rabbit antibody targeting p53. Anti-p53 Antibody (8U839) can be used in WB,ICC/IF. |
| Ig Type | IgG |
| 交叉反应 | Human,zebrafish |
| 验证活性 | 1. Western blot analysis of p53 on different cell lysates using anti-p53 antibody at 1/1,000 dilution. Positive control: Lane 1: 293T, Lane 2: 293. 2. ICC staining p53 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining p53 in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-5000; ICC/IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. P53 is found in increased amounts in a wide variety of transformed cells. P53 is frequently mutated or inactivated in about 60% of cancers. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 44/53 (Human), 41a (Zebrafish) kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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