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顶部生物活性储存和溶解信息计算器

Anti-MAPK10 Antibody (7M343)

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Anti-MAPK10 Antibody (7M343)
产品编号 TMAC-02287
别名 Stress-activated protein kinase JNK3, Stress-activated protein kinase 1b, SAPK1b, SAPK1B, PRKM10, Mitogen-activated protein kinase 10, MAPK 10, MAP kinase p49 3F12, MAP kinase 10, JNK3A, JNK3, EC 2.7.11.24, c-Jun N-terminal kinase 3

Anti-MAPK10 Antibody (7M343) 是一种 Rabbit 抗体，靶向 MAPK10。Anti-MAPK10 Antibody (7M343) 可用于 WB,ICC/IF,FCM。

Anti-MAPK10 Antibody (7M343)

Anti-MAPK10 Antibody (7M343)

Rating icon 还可以
Anti-MAPK10 Antibody (7M343)
产品编号 TMAC-02287 别名 Stress-activated protein kinase JNK3, Stress-activated protein kinase 1b, SAPK1b, SAPK1B, PRKM10, Mitogen-activated protein kinase 10, MAPK 10, MAP kinase p49 3F12, MAP kinase 10, JNK3A, JNK3, EC 2.7.11.24, c-Jun N-terminal kinase 3

Anti-MAPK10 Antibody (7M343) 是一种 Rabbit 抗体，靶向 MAPK10。Anti-MAPK10 Antibody (7M343) 可用于 WB,ICC/IF,FCM。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-MAPK10 Antibody (7M343) is a Rabbit antibody targeting MAPK10. Anti-MAPK10 Antibody (7M343) can be used in WB,ICC/IF,FCM.
别名Stress-activated protein kinase JNK3, Stress-activated protein kinase 1b, SAPK1b, SAPK1B, PRKM10, Mitogen-activated protein kinase 10, MAPK 10, MAP kinase p49 3F12, MAP kinase 10, JNK3A, JNK3, EC 2.7.11.24, c-Jun N-terminal kinase 3
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of JNK3 on 293T cells lysates using anti-JNK3 antibody at 1/1,000 dilution.
2. ICC staining JNK3 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining JNK3 in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining JNK3 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. Flow cytometric analysis of Jurkat cells with JNK3 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
WB
ICC/IF
FCM
推荐剂量
WB: 1:500; ICC/IF: 1:100-500; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield 10 isoforms through alternative mRNA splicing, including JNK1a1,JNK1b1, JNK2a1, JNK2b1, and JNK3a1, which represent the p46 isoforms, and JNK1a2, JNK1b2, JNK2a2, JNK2b2, and JNK3b2, which represent the p54 isoforms.JNKs coordinate cell responses to stress and influence regulation of cell growth and transformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. JNK3 (MK10, MAPK10, PRKM10) is activated by pro-inflammatory cytokines and environmental stresss by phosphorylating transcription factors such as c-Jun and ATF2. This is important for AP-1 transcriptional activity regulation. JNK3 is crucial for neuronal apoptosis (stress-induced).
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P53779
化学信息
分子量Theoretical: 53 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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