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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-KMT3B Polyclonal Antibody

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货号 TMAB-08139

Anti-KMT3B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 KMT3B。Anti-KMT3B Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-KMT3B Polyclonal Antibody

Anti-KMT3B Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08139

Anti-KMT3B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 KMT3B。Anti-KMT3B Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-KMT3B Polyclonal Antibody is a Rabbit antibody targeting KMT3B. Anti-KMT3B Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Chromosome (Probable).
组织特异性Expressed in the fetal/adult brain, kidney,skeletal muscle, spleen, and the thymus, and faintly in the lung.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human KMT3B/NSD1/ARA267
抗原种属
Human
基因名称
NSD1
基因ID
64324
蛋白名称
Histone-lysine N-methyltransferase, H3 lysine-36 specific
Uniprot ID
Q96L73
功能
Histone methyltransferase. Preferentially methylates'Lys-36' of histone H3 and 'Lys-20' of histone H4 (in vitro).Transcriptional intermediary factor capable of both negatively orpositively influencing transcription, depending on the cellularcontext.
化学信息
分子量Theoretical: 296 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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