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NKG2A/CD159a Protein, Cynomolgus/Rhesus, Recombinant (hFc)

NKG2A/CD159a Protein, Cynomolgus/Rhesus, Recombinant (hFc)

产品编号 TMPY-03686
别名: killer cell lectin-like receptor subfamily C, member 1

NKG2A/CD159a Protein, Cynomolgus/Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 30.8 kDa and the accession number is Q68VD2.

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NKG2A/CD159a Protein, Cynomolgus/Rhesus, Recombinant (hFc)
规格 价格/CNY 货期 数量
100 μg ¥ 4,470 现货
200 μg ¥ 7,900 5日内发货
500 μg ¥ 16,710 5日内发货
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产品目录号及名称: NKG2A/CD159a Protein, Cynomolgus/Rhesus, Recombinant (hFc) (TMPY-03686)
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生物活性 Testing in progress
产品描述 NKG2A/CD159a Protein, Cynomolgus/Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 30.8 kDa and the accession number is Q68VD2.
种属 Cynomolgus,Rhesus
表达系统 HEK293 Cells
标签 N-hFc
蛋白编号 Q68VD2
别名 killer cell lectin-like receptor subfamily C, member 1
蛋白构建 The cynomolgus / rhesus KLRC1 (NP_001271106.1/Q9MZJ2) (Pro94-Leu233) was expressed with the Fc region of Human IgG1 at the N-terminus. Cynomolgus and Rhesus KLRC1 sequences are identical.
蛋白纯度 > 85 % as determined by SDS-PAGE

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分子量 30.8 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 NKG2, also known as NKG2A(CD159A), is a member of the killer cell lectin-like receptor family. This family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this family are characterized by the type II membrane orientation and the presence of a C-type lectin domain. NKG2 contains 1 C-type lectin domain and forms a complex with another family member, KLRD1/CD94. It is expressed only in NK-cells, but not in T-cells or B-cells. It has been shown that NKG2 represents a family of related cDNA clones, designated NKG2A, NKG2B, NKG2C, and NKG2D, which encode type 2 integral membrane proteins (extracellular C-terminus) containing a C-type lectin domain. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NKG2 functions as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

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Keywords

NKG2A/CD159a Protein, Cynomolgus/Rhesus, Recombinant (hFc) killer cell lectin-like receptor subfamily C, member 1 recombinant recombinant-proteins proteins protein

 

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